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Peer reviewed publications
141. Joglekar MV, Kaur S, Pociot F and Hardikar AA (2024) Predicting future type 1 diabetes using dynamic biomarkers from the circulation
The Lancet D&E - (in press)
140. Nhan HTP, Joglekar MV, Wong WKM, Nassif NT, Simpson AM and Hardikar AA (2024) The role of short-chain fatty acids on insulin sensitivity: a systematic review and meta-analysis Nutrition Reviews 2024 Jan 10;82(2):193-209. doi: 10.1093/nutrit/nuad042.PMID: 37290429
2023
139. Shihana F, Joglekar MV, Schwantes-An TH, Hardikar AA, Seth D. (2024) MicroRNA Signature Panel Identifies Heavy Drinkers with Alcohol-Associated Cirrhosis from Heavy Drinkers without Liver Injury. Biology (Basel) 2023 Oct 8;12(10):1314. doi: 10.3390/biology12101314.PMID: 37887024
138. O'Rourke MB, Januszewski AS, Sullivan DR, Lengyel I, Stewart AJ, Arya S, Ma RC, Galande S, Hardikar AA, Joglekar MV, Keech AC, Jenkins AJ, Molloy MP. (2023) Optimised plasma sample preparation and LC-MS analysis to support large-scale proteomic analysis of clinical trial specimens: Application to the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) trial. Proteomics Clin Appl. 2023 May;17(3):e2200106. doi: 10.1002/prca.202200106. Epub 2023 Mar 22. PMID: 36891577
137. Da'as S, Ahmed I, Hasan W, Abdelrahman D, Aliyev E, Nisar S, Bhat AA, Joglekar M, Hardikar A, Fakhro K, Akil AA (2023) The Link Between Glycemic Control Measures and Eye Microvascular Complications in a Clinical Cohort of Type 2 Diabetes with MicroRNA-223 Signature. Journal of Translational Medicine Accepted for publication January 16, 2023
136. Wong WKM, Sara M, Farr RJ, Kunte PS, Hardikar HP, Yajnik CS, Hardikar AA* and Joglekar MV* (2023) MicroRNA profiling from tears as a potential non-invasive method for early detection of diabetes retinopathy. Methods Mol Biol. (Diabetic Retinopathy series) Accepted for publication January 24, 2023
2022
135. Wong KK, Cheng F, Lim CKP, Tam CHT, Tutino G, Yuen LY, Wang CC, Hou Y, Chan MHM, Ho CS, Joglekar MV, Hardikar AA, Jenkins AJ, Metzger BE, Lowe WL Jr, Tam WH, Ma RCW.Early emergence of sexual dimorphism in offspring leukocyte telomere length was associated with maternal and children's glucose metabolism-a longitudinal study. BMC Medicine. 2022 Dec 20;20(1):490. doi: 10.1186/s12916-022-02687-5.PMID: 36536359
134. Alvandi E, Wong WKM, Joglekar MV, Spring KJ, Hardikar AA. (2022) Short-chain fatty acid concentrations in the incidence and risk-stratification of colorectal cancer: a systematic review and meta-analysis.2022 BMC Medicine. 2022 Oct 3;20(1):323. doi: 10.1186/s12916-022-02529-4. PMID: 36184594
133. Dalgaard L, Sørensen A, Hardikar A, and Joglekar M (2022) The microRNA-29 family – role in metabolism and metabolic disease. Accepted for publication (June 2022) Am. J Physiol - Cell Physiol
132. Prasad SN, Anderson SR, Hardikar AA, Joglekar MV, Bansal V and Ramanathan R (2022) A bimetallic nanozyme catalyst created using galvanic replacement reaction for smartphone-based monitoring of urine glucose (accepted for publication May 2022). Biosensors and Bioelectronics
131. Wong KK, Cheng F, Mao D, Lim CKP, Tam CHT, Wang CC, Yuen LY, Chan MHM, Ho CS, Joglekar MV, Hardikar AA, Jenkins AJ, Metzger BE, Lowe WL Jnr., Tam WH, Ma RCW (2022) Vitamin D levels during pregnancy are associated with offspring telomere length: a longitudinal mother-child study (accepted for publication May 2022). J Clin Endocrinol Metab
130. Wong WKM*, Thorat V*, Joglekar MV*, Dong CX, Lee H, Chew YV, Bhave A, Hawthorne WJ, Engin F, Pant A, Dalgaard LT, Bapat S# and Hardikar AA# (2022) Analysis of half a billion datapoints across ten machine-learning algorithms identify key elements associated with insulin transcription in human pancreatic islet cells. (* equal first author, # equal senior authors). Mar 23;13:853863. doi: 10.3389/fendo.2022.853863. eCollection 2022. PMID: 35399953 Frontiers in Endocrinology
129. Joglekar MV, Kunte PS, Wong WKM, Bhat D, Satoor SN, Patil RR, Karandikar M, Fall C, Yajnik CS#, Hardikar AA# (2022) Circulating microRNAs from early childhood and adolescence are associated with pre-diabetes at 18 years of age in women from the PMNS cohort. Apr 22:1-6. doi: 10.1017/S2040174422000137 PMID: 35450554 J Dev Origins of Health in Adults (J DOHaD)
128. Shultz SR, Taylor CJ, Aggio-Bruce R, O’Brien WT, Sun M, Cioanca AV, Symons GF, Hardikar AA, Joglekar MV, Costello DM, O’Brien TJ, Natoli R, and McDonald SJ (2022) Decrease in plasma miR-27a and miR-221 after concussion in Australian football players. Feb 28; 17: 11772719221081318. doi: 10.1177/11772719221081318. eCollection 2022. PMID: 35250259 Biomarker Insights
127. Cheng F, Luk AO, Shi M, Huang C, Jiang G, Yang A, Wu H, Lim CKP, Tam CHT, Fan B, Lau ESH, Ng ACW, Wong KK, Carroll L, Lee HM, Kong AP, Keech AC, Chow E, Joglekar MV, Tsui SKW, So WY, So HC, Hardikar AA, Jenkins AJ, Chan JCN, Ma RCW (2022) Shortened Leukocyte Telomere Length Is Associated With Glycemic Progression in Type 2 Diabetes: A Prospective and Mendelian Randomization Analysis. Mar 1;45(3):701-709. doi: 10.2337/dc21-1609. PMID: 35085380 Diabetes Care.
126. Joglekar MV°, Sahu S°, Wong WKM°, Satoor SN, Dong CX, Farr RJ, Williams MD, Pandya P, Jhala G, Yang SNY, Chew YV, Hetherington N, Thiruchevlam D, Mitnala S, Rao GV, Reddy DN, Loudovaris T, Hawthorne WJ, Elefanty AG, Joglekar VM, Stanley EG, Martin D, Thomas HE, Tosh D, Dalgaard LT and Hardikar AA* (2022) A pro-endocrine pancreatic islet transcriptional program established during development is retained in human gallbladder epithelial cells. 13(5):1530-1553.e4. doi: 10.1016/j.jcmgh.2022.01.008. Epub 2022 Jan 12. PMID: 35032693 Cell Mol Gastroenterol Hepatol
125. Cheng F, Luk AO, Wu H, Tam CHT, Lim CKP, Fan B, Jiang G, Carroll L, Yang A, Lau ESH, Ng ACW, Lee HM, Chow E, Kong APS, Keech AC, Joglekar MV, So WY, Hardikar AA, Chan JCN, Jenkins AJ, Ma RCW. (2022) Relative leucocyte telomere length is associated with incident end-stage kidney disease and rapid decline of kidney function in type 2 diabetes: analysis from the Hong Kong Diabetes Register. Feb;65(2):375-386. doi: 10.1007/s00125-021-05613-1. Epub 2021 Nov 22. PMID: 34807303 Diabetologia.
2021
124. Saini V, Joglekar MV, Wong WKM, Jiang G, Nassif NT, Simpson AM, Ma RCW, Dalgaard LT, Hardikar AA (2021) Manipulating cellular microRNAs and analyzing high-dimensional gene expression data using machine learning workflows. STAR Protoc. 2021 Oct 23;2(4):100910. doi: 10.1016/j.xpro.2021.100910. eCollection 2021 Dec 17. PMID: 34746868
123. Cheng F et al.... Ma RCW (2021) Relative Leukocyte Telomere Length Predicts Incident End-Stage Kidney Disease and Rapid Loss of Kidney Function in Type 2 Diabetes – Analysis from the Hong Kong Diabetes Register. Diabetologia (Accepted for publication)
122. Scott ES, Januszewski AS, Carroll LM, Fulcher GR, Joglekar MV, Hardikar AA, Jones TW, Davis EA, Jenkins AJ (2021) Continuous subcutaneous insulin infusion alters microRNA expression and glycaemic variability in children with type 1 diabetes. Sci Rep. 17;11(1):16656. doi: 10.1038/s41598-021-95824-8. PMID: 34404828 121. Januszewski AS*, Cho YH*, Joglekar MV*, Farr RJ, Scott ES, Wong WKM, Carroll LM, Loh YW, Benitez-Aguirre PZ, Keech AC, O'Neal DN, Craig ME, Hardikar AA^, Donaghue KC^, Jenkins AJ^ (2021) Insulin micro-secretion in Type 1 diabetes and related microRNA profiles. Sci Rep. 11(1):11727. doi: 10.1038/s41598-021-90856-6. PMID: 34083567 (*equal first authors, ^equal senior authors) 120. Joglekar MV, Dong CX, Wong WKM, Dalgaard LT and Hardikar AA (2021) A birds' eye view of the dynamics of pancreatic beta-cell heterogeneity. Acta Physiologica. e13664. doi: 10.1111/apha.13664. PMID: 33884752
119. Wong WKMW*, Joglekar MV*, Saini V, Jiang G, Dong CX, Chaitarvornkit A, Maciag GJ, Gerace D, Farr RJ, Satoor SN, Sahu S, Sharangdhar T, Ahmed AS, Chew Y, Liuwantara D, Heng B, Lim CK, Hunter J, Januszewski AS, Sørensen AE, Akil AS, Gamble JR, Loudovaris T, Kay TW, Thomas HE, O’Connell PJ, Guillemin GJ, Martin D, Simpson AM, Hawthorne WJ, Dalgaard LT, Ma RCW and Hardikar AA (2021) Machine learning workflows identify a microRNA signature of insulin transcription in human tissues (*equal first authors) iScience. 24(4):102379. doi: 10.1016/j.isci.2021.102379 PMID: 33981968 118. Shihana F, Wong WKM, Joglekar MV, Mohamed F, Gawarammana IB, Isbister GK, Hardikar AA*, Seth D*, Buckley N* (2021) Urinary microRNAs as non-invasive biomarkers for toxic acute kidney injury in humans. (*equal senior authors) Sci Rep. 11(1):9165. doi: 10.1038/s41598-021-87918-0. PMID: 33911095 117. Joglekar MV, Wong WKM, Khan F, Georgiou HM, Shub A, Hardikar AA*, Lappas M,* (2021) Post-partum circulating microRNA enhance prediction of future type 2 diabetes in women with previous gestational diabetes (*: equal senior/corresponding authors). Diabetologia. 64(7):1516-1526. doi: 10.1007/s00125-021-05429-z. PMID: 33755745 116.Cheng F, Luk AO, Wu H, Kp Lim C, Carroll L, Ht Tam C, Fan B, Yang A, Sh Lau E, Cw Ng A, Man Lee H, Chow E, Kong AP, Keech AC, V Joglekar M, Yee So W, Jenkins AJ, Cn Chan J, Hardikar AA, Cw Ma R (2021) Shortened Relative Leukocyte Telomere Length is Associated with All-cause Mortality in Type 2 Diabetes- Analysis from the Hong Kong Diabetes Register. Diabetes Res Clin Pract. Jan 7:108649. doi:10.1016/ j.diabres. 2021.108649. Online ahead of print. PMID: 33422583 115. Joglekar MV, Patil RR, Satoor SN, Wong WKM, Karandikar MS, and Hardikar AA, (2021) Promoting pro-endocrine differentiation and graft maturation following surgical resection of the mouse pancreas (accepted for publication on September 08, 2019) Meth. Mol Biol. 114. Cheng F, Carroll L, Joglekar MV, Januszewski A, Wong KK, Hardikar AA*, Jenkins AJ*, Ma RCW* (2020) Diabetes, metabolic disease and telomere length (Accepted for publication October 08, 2020; *: equal senior/corresponding authors). The Lancet D&E Nov 26:S2213-8587(20)30365-X. doi: 10.1016/S2213-8587(20)30365-X. Online ahead of print. PMID: 33248477 2020 (Moved group from Sydney University to Western Sydney University, Australia) 113. Shihana F, Mohamed F, Joglekar MV, Hardikar AA, Seth D, Buckley NA (2020) Urinary versus serum microRNAs in human oxalic acid poisoning: contrasting signals and performance (Accepted for publication September 03, 2020). Toxicology Letters Nov 1;334:21-26. doi: 10.1016/j.toxlet.2020.09.003. Epub 2020 Sep 7. PMID: 32910981 112. Gamage HKAM, Chong RWW, Bucio-Noble D, Kautto L, Hardikar AA, Balld MS, Molloy MP, Packer NH, Paulsen IT (2020) Changes in dietary fibre intake in mice reveal associations between colonic mucin O-glycosylation and specific gut bacteria (Accepted for publication). Gut Microbes. Nov 9;12(1):1802209. doi: 10.1080/19490976.2020.1802209. PMID: 32991816 111. Cheng F, Luk AO, Tam CHT, Fan B, Wu H, Yang A, Lau ESH, Ng ACW, Lim CKP, Lee HM, Chow E, Kong AP, Keech AC, Joglekar MV, So WY, Jenkins A, Chan JCN, Hardikar AA and Ma RCW (2020) Shortened Relative Leukocyte Telomere Length is Associated with Prevalent and Incident Cardiovascular Complications in Type 2 Diabetes- Analysis from the Hong Kong Diabetes Register (Jul 13:dc200028. doi: 10.2337/dc20-0028. Online ahead of print. PMID: 32661111). Diabetes Care Sep;43(9):2257-2265. doi: 10.2337/dc20-0028. Epub 2020 Jul 13. PMID: 32661111 110. Joglekar MV, Satoor SN, Wong WKM, Cheng F, Ma RCW, Hardikar AA. (2020) An Optimised Step-by-Step Protocol for Measuring Relative Telomere Length. Methods Protoc. 2020 Apr 3;3(2):E27. doi: 10.3390/mps3020027. PMID: 32260112 109. Williams MD, Joglekar MV, Hardikar AA and Wong WKM (2020) Directed differentiation into insulin-producing cells using microRNA manipulation; 15: 1-4 (commentary) Open Medicine Jun 19;15(1):567-570. doi: 10.1515/med-2020-0170. eCollection 2020. PMID: 33336012 108. Barraclough JY, Joglekar MV, Januszewski AS, Martínez G, Celermajer DS, Keech AC, Hardikar AA and Patel S. (2020) A MicroRNA Signature in Acute Coronary Syndrome Patients and Modulation by Colchicine. J Cardiovasc Pharmacol Ther. 2020 May 1:1074248420922793. doi: 10.1177/1074248420922793. Online ahead of print. PMID: 32356454 107. Shihana F, Joglekar MV, Raubenheimer J, Hardikar AA, Buckley NA, Seth D (2020) Circulating human microRNA biomarkers of oxalic acid induced acute kidney injury Arch Toxicol. 94(5):1725-1737. doi: 10.1007/s00204-020-02679-5. PMID: 32086547 ------------------------------------------------------------------------------------------------------------------------------------------------------------------ 2019 106. Scott ES, McGrath RT, Januszewski AS, Calandro D, Hardikar AA, O’Neal DN, Fulcher GR, Jenkins AJ (2019) HbA1c Variability in Adults With Type 1 Diabetes on Continuous Subcutaneous Insulin Infusion (CSII) Therapy Compared To Multiple Daily Injection (MDI) Treatment (accepted for publication on December 02, 2019) BMJ Open 9(12):e033059. doi: 10.1136/bmjopen-2019-033059. PMID: 31888933
105. Barraclough J, Joan M, Joglekar M, Hardikar A and Patel S (2019) Prognostic utility of microRNAs in patients with acute coronary syndromes– A systematic review. Cells : 8(12):1572. doi: 10.3390/cells8121572.
104. Sørensen AE, Udesen PB, Maciag G, Geiger J, Saliani N, Januszewski A, Jiang G, Ma RC, Hardikar AA, Wissing MLM, Englund ALM and Dalgaard LT (2019) Hyperandrogenism and metabolic syndrome is associated with changes in serum-derived microRNAs in women with polycystic ovary syndrome (accepted for publication on October 14, 2019) Frontiers in Medicine (Translational Medicine) ;6:242. doi: 10.3389/fmed.2019.00242. eCollection 2019. PMID: 31737638
103. Bensellam M, Chan JY, Lee KL, Joglekar M, Hardikar A, Loudovaris T, Thomas H, Jonas JC, and Laybutt DR (2019) Phlda3 regulates beta-cell survival during stress. Scientific Reports 6;9(1):12827. doi: 10.1038/s41598-019-49289-5.
102. Wong WKM, Jiang G, Sørensen AE, Chew YV, Maynard CL, Liuwantara D, Williams L, O’Connell P, Dalgaard LT, Ma RC, Hawthorne WJ, Joglekar MV, and HardikarAA (2019) The long noncoding RNA MALAT1 predicts human pancreatic islet isolation quality; JCI insight pii: 129299. doi: 10.1172/jci.insight.129299. PMID: 31361602
101. Lappas M,Georgiou HM, Willcox J, Permezel M, Shub A, Maynard CL, Joglekar MV, Hardikar AA (2019) Postpartum circulating cell-free insulin DNA levels are higher in women with previous gestational diabetes mellitus who develop type 2 diabetes in later life. J Diabetes Res. 3264184. doi: 10.1155/2019/3264184..
100. Kim SY, Joglekar MV, Hardikar AA, Phan TH, Khanal D, Tharkar P, Limantoro C, Johnson J, Kalionis B and Chrzanowski W (2019) Placenta stem/stromal cell-derived extracellular vesicles for the treatment of lung diseases. Proteomics ; 19(17): e1800166. doi: 10.1002/pmic.201800166.
99. Udesen PB, Sørensen AE, JoglekarMV, Hardikar AA, Wissing MM, Englund AM, Dalgaard LT (2019) Levels of circulating insulin cell-free DNA in women with Polycystic Ovary Syndrome – a longitudinal cohort study. Rep Biol. Endocrinol 17(1):34. doi: 10.1186/s12958-019-0478-7.
98. Farr RJ, Wong WKM, Maynard C, Tersey SA, Mirmira RG, Hardikar AA and Joglekar MV (2019) Comparative analysis of diagnostic platforms for measurement of unmethylated / methylated insulin DNA. J Biol Meth 6(2). pii: e113. doi: 10.14440/jbm.2019.280.
97. Poddar A, Joglekar MV, Hardikar AA and Shukla R (2019) A novel gene delivery approach using metal organic frameworks in human islet-derived cells Meth. Mol. Biol; 2029:81-91. doi: 10.1007/978-1-4939-9631-5_7, PMID: 31273735.
96. Maynard CL, Wong WKM, Hardikar AA and Joglekar MV (2019) Droplet digital PCR for measuring absolute copies of gene transcripts in human islet-derived progenitor Cells Meth. Mol. Biol; 2029:37-48. doi: 10.1007/978-1-4939-9631-5_4, PMID: 31273732.
95. Slykerman R, Joglekar M, Hardikar A, Satoor S, Thompson JM, Jenkins AJ, Mitchell EA, Murphy R (2019) Maternal stress during pregnancy and small for gestational age birthweight are not associated with telomere length at 11 years of age. Gene 694:97-101. doi: 10.1016/j.gene.2019.01.017. Epub 2019 Feb 7.
94. Williams MD, Joglekar MV, Satoor SN, Wong WKM, Keramidaris E, Rixon A, O’Connell P, Hawthorne WJ, Mitchell GM and Hardikar AA (2019) Epigenetic and transcriptome profiling identifies a population of visceral adipose-derived progenitor cells with potential to differentiate into endocrine pancreatic lineage; Cell Transplantation 28(1):89-104. doi: 10.1177/0963689718808472. Epub 2018 Oct 30, PMID: 30376726. 2018 93. Joglekar MV, Sorensen A, Wong KM, Hardikar AA, Dalgaard LT (2018) Non-coding RNAs in islet β-cell maturation and development; Noncoding RNA 4(4). pii: E41. doi: 10.3390/ncrna4040041..
92. Joglekar MV, Wong WKM, Maynard C, Umrani MR, Martin D, Loudovaris T, Thomas HE, Dalgaard LT and Hardikar AA (2018) Expression of miR-206 in human islets and its role in glucokinase regulation. Am J Physiol - Endocrinol & Metab;315(4):E634-E637. doi: 10.1152/ajpendo.00152.2018 2017 91. Hakami NY, Ranjan AK, Hardikar AA, Dusting GJ, Peshavariya HM (2017) Role of NADPH Oxidase-4 in Human Endothelial Progenitor Cells. Frontiers in Physiology. 23;8:150. 90. Umrani MR, Joglekar MV, Somerville Glover E, Wong W and Hardikar AA (2017) Connexins and microRNAs: interlinked players in regulating islet function? Islets; 3;9(5):99-108 2016 89. Joglekar MV, Trivedi PM, Kay TW, Hawthorne WJ, O'Connell PJ, Jenkins AJ, Hardikar AA, Thomas HE. (2016) Human islet cells are killed by BID-independent mechanisms in response to FAS ligand Apoptosis; 21(4):379-89. doi: 10.1007/s10495-016-1212-y.PMID: 26758067
88. Joglekar MV, Januszewski AS, Jenkins AJ, Hardikar AA. (2016) Circulating microRNA Biomarkers of Diabetic Retinopathy. Diabetes. ;65(1):22-4. doi: 10.2337/dbi15-0028. PMID: 26696637 2015 87. Jenkins AJ, Joglekar MV, Hardikar AA, Keech AC, O'Neal DN, Januszewski AS (2015) Biomarkers in Diabetic Retinopathy. Rev. Diabet Studies; 12(1-2):159-95. doi: 10.1900/RDS.2015.12.159. Epub 2015 Aug 10.PMID: 26676667
86. Farr RJ, Joglekar MV, Hardikar AA.(2015) Circulating microRNAs in Diabetes Progression: Discovery, Validation, and Research Translation. EXS. 2015;106:215-44. doi: 10.1007/978-3-0348-0955-9_10. PMID: 26608206
85. Kim KW, Ho A, Alshabee-Akil A, Hardikar AA, Kay TW, Rawlinson WD, Craig ME.(2015) Coxsackievirus B5 Infection Induces Dysregulation of MicroRNAs Predicted to Target Known Type 1 Diabetes Risk Genes in Human Pancreatic Islets. Diabetes *. 2015 Nov 11. pii: db150956.
* Also special commentary in Nature Reviews - Endocrinology and Metabolism
84. Hardikar AA1,°, Satoor SN°, Karandikar MS°, Joglekar MV° et al.. (2015) Susceptibility to obesity and diabetes following multigeneration undernutrition is not reversed by two generations of nutrient availability. Cell Metabolism (PMID: 26166746); 1 AAH – First and corresponding author, ° equal contribution amongst 19 authors (Cover story).
83. Farr RJ, Januszewski AS, Joglekar MV, Liang H, McAulley AK, Hewitt AW, Thomas HE, Loudovaris T, Kay TW, Jenkins A, Hardikar AA (2015) A comparative analysis of high-throughput platforms for validation of a circulating microRNA signature in diabetic retinopathy. Scientific Reports. 2;5:10375. www.nature.com/srep; doi: 10.1038/srep10375.
82. Wong W, Farr RJ, Joglekar MV, Januszewski AS, Hardikar AA (press) Probe-based real-time PCR approaches for quantitative measurement of microRNAs. J Visual Exp 14;(98). doi: 10.3791/52586
81. Liu J, Joglekar MV, Sumer H, Hardikar AA, Teede H, Verma PJ (2015) Integration-Free Human Induced Pluripotent Stem Cells from Type 1 Diabetes Patient Skin Fibroblasts Show Upregulation of Pancreas-Specific microRNAs, Cell Medicine; 7(1): 15-24 2014 80. Hardikar AA, Farr RJ, Joglekar MV (2014) Circulating microRNAs: Understanding the limits for quantitative measurement by real-time PCR J Am Heart Assoc. 3(1): e000792. doi: 10.1161/JAHA.113.000792.
79. Williams MD, Wong W, Rixon A, Satoor SN, Hardikar AA, Joglekar MV. (2014) Pdx1 (GFP/w) mice for isolation, characterization, and differentiation of pancreatic progenitor cells. Meth. Mol. Biol, 1194:271-88. doi: 10.1007/978-1-4939-1215-5_15.
78. Satoor SN, Patil DP, Kristensen HD, Joglekar MV, Shouche Y, Hardikar AA. (2014) Manipulation and assessment of gut microbiome for metabolic studies. Meth. Mol. Biol 1194:449-69. doi: 10.1007/978-1-4939-1215-5_26. 2013 77. Hardikar AA: on behalf of the RAPID Study group (2013) microRNAs in Pancreatic Beta Cells: from Cradle to the Grave Pediatric Endocrinology Reviews ;11(1):14-20.
76. Sundrani DP, Reddy US, Joshi AA, Mehendale SS, Chavan-Gautam PM, Hardikar AA, Chandak GR, Joshi SR (2013) Differential placental methylation and expression of VEGF, FLT-1 and KDR genes in human term and preterm preeclampsia. Clinical Epigenetics. 26;5(1):6. doi: 10.1186/1868-7083-5-6.
75. Satoor SN and Hardikar AA (2013) Maternal nutrition, nutrient transfer & foetal pancreas development. Ind J Med Res.;137(2):249-50. 2012 (Moved group from Melbourne to Sydney University, Sydney, Australia) 74. Hardikar AA, Walker MD, Lynn F (2012) Non-codimng RNAs. Exp Diabetes Res. 629249. doi: 10.1155/2012/629249.
73. Ranjan AK, Joglekar MV, Atre AN, Patole M, Bhonde RR and Hardikar AA (2012) Simultaneous Imaging of microRNA / mRNA Territories with Protein Territory in Mammalian Cells at Single Cell Resolution. RNA Biology 9:7, 949-53. doi: 10.4161/rna.20484
72. Ranjan AK, Joglekar MV, Atre AN, Patole M, Bhonde RR and Hardikar AA (2012) Cellular detection of multiple antigens at single cell resolution using antibodies generated from the same species. J Imm Methods; 379(1-2):42-7. doi: 10.1016/ j.jim.2012.02.018
71. Joglekar MV and Hardikar AA (2012) Isolation, characterization and expansion of islet-derived progenitor cells. Meth. Mol. Biol 879:351-66. doi: 10.1007/978-1-61779-815-3_21.
70. Kumar U, Ranjan AK, Chandrashekhar S, Hardikar AA, Pundle A and Poddar P. (2012) Green approach towards size controlled synthesis of biocompatible antibacterial metal nanoparticles in aqueous phase using lysozyme. Current Nanoscience 8(1), 130-140(11) -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2011 69. Vaithilingam V, Quayum N, Joglekar MV, Jensen J, Hardikar AA, Oberholzer J, Guillemin GJ, PhD, Tuch BE (2011) Effect of alginate encapsulation on the cellular transcriptome of human islets. Biomaterials 32(33):8416-25
68. Satoor SN, Puranik AS, Kumar S, Williams MD, Ghale M, Rahalkar A, Karandikar MS, Shouche Y, Patole M, Bhonde RR, Yajnik CS and Hardikar AA (2011) Location, location, location: Beneficial effects of autologous fat transplantation. Scientific Reports 2011;1:81. (http://www.nature.com/srep/2011/110902/srep00081/full/srep00081.html)
67. Ansarullah, Bhavna Bharucha, Mitesh Dwivedi, Naresh C Laddha, Rasheedunnisa Begum, Hardikar AA and A V Ramachandran (2011) Antioxidant rich flavonoids from Oreocnide integrifolia enhance glucose uptake and insulin secretion and protects pancreatic beta-cells from streptozotocin insult. BMC Comp Alt Med 12;11:126. doi: 10.1186/1472-6882-11-126.
66. Ansarullah, Bhavna Bharucha, Malati Umarani, Mitesh Dwivedi, Naresh C Laddha, Rasheedunissa Begum, Hardikar AA, and Ramachandran A.V (2011) Oreocnide integrifolia flavonoids augment reprogramming for islet neogenesis and ß-cell regeneration in pancreatectomized BALB/c mice Evid-Based Complement Alternat Med 260467. doi: 10.1155/2012/260467.
65. Forster N, Penington A, Hardikar AA, Palmer J, Hussey A, Taj J, Morrison W, Feeney S (2011) A prevascularised tissue engineering chamber supports growth and function of islets and progenitor cells in diabetic mice, Islets 3(5):271-83.
64. Williams MD, Mitchell GM and Hardikar AA (2011) Stem cells: Epigenetic basis of differentiation Open Stem Cells 3:28-33
63. Phadnis SM, Joglekar MV, Dalvi1 MP, Muthyala S, Nair PD, Ghaskadbi SM, Bhonde RR and Hardikar AA (2011) Human bone marrow-derived mesenchymal cells differentiate and mature into endocrine pancreatic lineage in vivo. Cytotherapy 13(3): 279-293 Cover story
62. Ansarullah, Jayaraman S, Hardikar AA and Ramachandran AV (2011) Influence of Oreocnide integrifolia (Gaud.) Miq on IRS-1, Akt and Glut-4 in Fat-Fed C57BL/6J Type 2 Diabetes Mouse Model. Evid-Based Complement Alternat Med 13 (3): 1-9 doi:10.1093/ecam/neq014. 2010 61. Parekh VS, Umrani MR and Hardikar AA (2010) Taurine supports preservation of pro-endocrine cell types in human umbilical cord blood-derived mononuclear cells during cryostorage. Transplant Proc, 42(10):4619-21
60. Joglekar MV and Hardikar AA (2010) Epithelial-to-mesenchymal transition in pancreatic islet beta cells. Cell Cycle 15;9(20):4077-9
59. Chayosumrit M, Hardikar AA and Sidhu K. Role of the Glucagon-like Peptide-1 Receptor Agonist in Maintaining Pluripotency in Human Embryonic Stem Cells. Open Stem Cells 2011; 3: 11-22
58. Joglekar MV, Wei CJ and Hardikar AA (2010) Quantitative estimation of multiple microRNAs and mRNAs from a single cell. Cold Spring Harb. Protocols 1;2010(8):pdb.prot5478. doi: 10.1101/pdb.prot5478 Cover story
57. Wu Y, Li J, Saleem S, Yee S, Hardikar AA, and Wang R (2010) C-Kit and stem cell factor regulate PANC-1 cell differentiation to insulin- and glucagon-producing cells. Lab Investigation 90(9):1373-84
56. Khandwekar AP, Patil DP, Hardikar AA, Shouche YS, Doble M. (2010) In vivo modulation of foreign body response on polyurethane by surface entrapment technique. J Biomed Mater Res. 95(2):413-23
55. Sasikala M, Swapna G, Pavan K, Rao GV, Hardikar AA and Reddy DN (2010) Reduced expression of pdx-1 correlates with decreased beta cell function in chronic pancreatitis. Pancreas 39(6):856-62
54. Lee J, Jo J, Hardikar AA, Periwal V and Rane SG (2010) Cdk4 regulates recruitment of quiescent β-cells and ductal epithelial progenitors to reconstitute β-cell mass PLoS ONE 13;5(1):e8653 2009 (Moved group from Pune, India to Melbourne, Australia) 53. Phadnis SM, Ghaskadbi SM, Hardikar AA, Bhonde RR (2009) Mesenchymal stem cells derived from bone marrow of diabetic patients portrait unique markers influenced by the diabetic microenvironment. Rev Diabet Stud. 6(4):260-70.
52. Ranjan AK, Kumar U, Hardikar AA, Poddar P, Nair PD, Hardikar AA (2009) Human blood vessel-derived endothelial progenitors for endothelialization of small diameter vascular prosthesis. PLoS ONE 4(11):e7718.PMID: 19890388
51. Joglekar MV, Patil D, Joglekar VM, Rao GV, Reddy DN, Sasikala M, Shouche Y and Hardikar AA (2009) The miR-30 Family microRNAs Confer Epithelial Phenotype to Human Pancreatic Cells. Islets 1(2): 137 - 147. Cover story
50. Parekh VS, Joglekar MV and Hardikar AA (2009) Differentiation of human umbilical cord blood derived mononuclear cells to endocrine pancreatic lineage. Differentiation 78(4):232-40. Cover story
49. Joglekar MV, Joglekar VM, Joglekar SV and Hardikar AA (2009), Human fetal pancreatic insulin-producing cells proliferate in vitro. J. Endocrinology 201(1):27-36, Epub 2009 May 6 Cover story
48. Sahu S*, Joglekar MV*, Dumbre R, Phadnis SM, Tosh D and Hardikar AA, (2009) Islet-like cell clusters occur naturally in human gall bladder and are retained in diabetic conditions J Cell Mol Med: 13(5):999-1000; *: equal first authors.
47. Joglekar MV, Joglekar VM and Hardikar AA (2009) Expression of islet-specific microRNAs during human pancreatic development. Gene Exp Patterns; 9(2): 109-113.
46. Dalvi MP, Umrani MR, Joglekar MV, Hardikar AA (2009) Human pancreatic islet progenitor cells demonstrate phenotypic plasticity in vitro. J Biosci. 34(4):523-8.
45. Ranjan AK, Joglekar MV and Hardikar AA (2009) Endothelial cells in pancreatic islet development and function Islets 1(1); 2 – 9
44. Kode JA, Mukherjee S, Joglekar MV and Hardikar AA (2009) Mesenchymal Stem cells: Immunobiology and role in immunomodulation and tissue regeneration. Cytotherapy : 11(4):377-91 2007 43. Joglekar MV, Parekh VS, Mehta S, Bhonde RR and Hardikar AA (2007) MicroRNA Profiling of Developing and Regenerating Pancreas Reveal Post-transcriptional Regulation of Neurogenin3. Developmental Biology 311(2): 603-612
42. Joglekar MV, Parekh VS and Hardikar AA (2007) New Pancreas from Old: Microregulators of Pancreas Regeneration Trends Endocrinol Metab 18(10):393-400. Cover citation. 2006 41. Phadnis SM*, Joglekar MV*, Venkateshan V, Ghaskadbi SM, Hardikar AA, Bhonde RR. (2006) Human umbilical cord blood serum promotes growth, proliferation, as well as differentiation of human bone marrow-derived progenitor cells. In Vitro Cell Dev Biol . 42(10):283-6.
40. Hardikar AA, Lees JG, Sidhu KS, Colvin E and Tuch BE; Stem-Cell Therapy for Diabetes Cure: How Close Are We? (2006) Current Stem Cell Research and Therapy: 1:425-436 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2005 and before establishing this group (post-doctoral training AAH) 39. Gershengorn MC, Geras-Raaka E, Hardikar AA, Raaka BM. (2005) Are better islet cell precursors generated by epithelial-to-mesenchymal transition? Cell Cycle. 4:380-382.
38. Gershengorn MC, Hardikar AA, Wei C, Geras-Raaka E, Marcus-Samuels B, Raaka BM (2004) Epithelial-to-Mesenchymal Transition Generates Proliferative Human Islet Precursor Cells. Science 306:2261-2264.
37. Hardikar AA (2004) Pancreas regeneration: Generating new pancreas from old. Trends Endocrinol Metab. 15:198-203 Cover story
36. Hardikar AA, Marcus-Samuels B, Geras-Raaka E, Raaka BM, Gershengorn MC (2003) Human pancreatic precursor cells secrete FGF2 to stimulate clustering into hormone-expressing islet-like cell aggregates. Proc Natl Acad Sci U S A. 100(12): 7117-7122.
35. Hardikar AA, Wang XY, Williams LJ, Kwok J, Wong R, Yao M, Tuch BE. (2002) Functional maturation of fetal porcine beta-cells by glucagon-like peptide 1 and cholecystokinin. Endocrinology; 143:3505-3514.
34. Merezek S, Hardikar AA, Yajnik CS, Remacle C and Reusens B (2001) Intra-uterine protein malnutrition and diabetes: the role of sulphur amino acids. J Endocrinol; 171:299-308.
33. Hardikar AA, Risbud MV, Remacle C, Reusens B, Hoet JJ, Bhonde RR. (2001) Islet cryopreservation: improved recovery following taurine pretreatment. Cell Transplant; 10:247-253.
32. Hardikar AA, Nath BB. (2001) Chromosomal polymorphism is associated with nematode parasitism in a natural population of a tropical midge. Chromosoma; 110: 58-64.
31. Risbud MV, Hardikar AA, Bhat SV, Bhonde RR. (2000) pH-sensitive freeze-dried chitosan-polyvinyl pyrrolidone hydrogels as controlled release system for antibiotic delivery. J Control Release; 68: 23-30.
30. Hardikar AA, Risbud MV, Bhonde RR. (2000) Improved post-cryopreservation recovery following encapsulation of islets in chitosan-alginate microcapsules. Transplant Proc; 32: 824-5.
29. Risbud M, Hardikar A, Bhonde R. (2000) Growth modulation of fibroblasts by chitosan-polyvinyl pyrrolidone hydrogel: implications for wound management? J Biosci ; 25: 25-31.
28. Risbud M, Hardikar A, Bhonde R. (2000) Chitosan-polyvinyl pyrrolidone hydrogels as candidate for islet immunoisolation: in vitro biocompatibility evaluation. Cell Transplant; 9 : 25-31.
27. Hardikar AA, Bhonde RR. (1999) Modulating experimental diabetes by treatment with cytosolic extract from the regenerating pancreas. Diabetes Res Clin Pract; 46: 203-11.
26. Hardikar AA, Karandikar MS, Bhonde RR. (1999) Effect of partial pancreatectomy on diabetic status in BALB/c mice. J Endocrinol ; 162: 189-195.
25. Hardikar AA, Risbud MV and Bhonde RR (1999) A simple microcapsule generator design for islet encapsulation, J. Biosci. 24 (3): 371 - 376. Editorial /commentaries:
24. McGowan EM, Simpson A, McManaman J, Boonyaratanakornkit V, Hardikar AA (2015) Hijacking of Endocrine and Metabolic Regulation in Cancer and Diabetes. Biomed Res Int.:386203. doi: 10.1155/2015/386203. Epub 2015 Jul 9.
23. Hardikar AA, Walker M, Lynn FC (2013) Non-coding RNAs (Editorial) J Diabetes Res. (2012)
22. Hardikar A (2013) microRNAs: small regulators of human disease. Non-codingRNAs in Endocrinology
21. Satoor SN and Hardikar AA (2013) Maternal nutrition, nutrient transfer and foetalpancreas development. Invited commentary in press In J Med Res
20. Joglekar MV, Parekh VS and Hardikar AA (2011) microRNAs in endocrine pancreas development, differentiation and disease. In J Exp. Biol. (invited article in press)
19. Hardikar AA and Tosh D (2009) Commentary: β-cells in the lab. Nature India, doi 10:1038/nindia.2009.160 (http://www.nature.com/nindia/2009/090625/full/nindia.2009.160.html)
18. Sahu S, Tosh D and Hardikar AA (2009) Commentary: New sources of beta-cells for treating diabetes. J. Endocrinology: 202(1):13-6
17. Hardikar A, (2004) Role of Incretins in Pancreas Growth and Development (Editorial) J Pancreas 5(6):454-456.
Chapters in books:
16. Sahu S, Joglekar M, Yang S and Hardikar AA (2011) Gallbladder-derived islet stem cells, In "Stem Cells", ISBN: 978-953-307-412-2. Open Access Publishers, Vienna, Austria.
15. Joglekar MV and Hardikar AA (2013) Human fetal pancreatic progenitor cells in: Clinical issues of fetal tissue transplantation in medicine. Chapter 18, pp 237-249. Editor: Phillip Stubblefield and Niranjan Bhattacharya. Publisher: Springer
14. Lie D, Chayosumrit M, Hardikar A and Sidhu K (2010) Puluripotent stem cells and diabetes: Basic Science to Clinical Applications in: Frontiers in pluripotent stem cells research: Bench-to-Bedside Publisher: Betham Press, Editor: K Sidhu
13. Joglekar MV, Ranjan AK and Hardikar AA (2009) Pancreas development and regeneration. “In Stem cells: Organogenesis and Cancer” Editor: Dr. SR Singh, Book Editor & Managing Editor: Research Signpost/ Transworld Research Network press (http://www.ressign.com/). Frontiers in Bioscience, NIH, USA
12. Hardikar AA and Gershengorn MC (2003) Chapter 51: ‘Stem Cells’ in 3rd edition of ‘Diabetes Mellitus: A Fundamental and Clinical Text’, edited by: Dr. Derek LeRoith, Simeon I. Taylor and Jerrold M. Olefsky.
11. Shukla R, Risbud MR, Hardikar AA, Bhonde RR, (2004) Chitosan and chitin derivatives in islet immunoisolation and transplantation. In “Chitin and Chitosan: Opportunities and Challenges” Chapter 15, p 211-222, eds; Dutta PK
10. Wong W, Hardikar AA and Joglekar MV (2017) Generation of human islet progenitor cells via epithelial to mesenchymal transition, in Pancreatic Islet Biology, Springer Humana press, eds Hardikar A, pp217-240.Books:
9. “Pancreatic Islet Biology” (2016). Chief Editor: Hardikar AA, Publisher: Springer press, USA, ISSN 2196-8985, ISBN: 978-3-319-45305-7 (print version) / 978-3-319-45307-1. (e-book version). A textbook for diabetes researchers with 12 chapters from 45 authors over 336 pages of text.
8. “Methods in Molecular Biology: Progenitor Cells” (2019) Co-editor with Chief Editor Dr. Mugdha Joglekar, University of Sydney for a book in the well-known Methods in Molecular Biology book series published by Springer Press, USA. Resources:
7. Wong W, Joglekar MV, Chew Y, Hawthorne WJ, Hardikar AA (2019) Human islets of varying quality: the good, the (not so) bad and the ugly; This collection represents whole transcriptome datasets for human islets that were stratified to high quality (Group 1), intermediary quality (Group 2) and poor quality (Group 3) islets (Wong WKM et al JCI Insight 2019). Series Accession: GSE134068ID: 200134068. Intellectual Property (filed)
6. Hardikar AA, Joglekar MV and Januszewski AS (2017) Intracellular microRNA Signatures of Insulin Production: WO2019000017 A1.
5. Hardikar AA, Joglekar MV and Januszewski AS (2017) Circulating microRNA signatures of islet beta cell death and progression to diabetes: WO2019000015 A1.
4. Hardikar AA, Wong W, Joglekar MV and Hawthorne WJ (2019) A long non-coding RNA that predicts islet isolation outcome (IP Australia # 2019202308).
3. Patel S, Hardikar A, Barraclough J and Keech AC: A miRNA signature to assess treatment efficacy in acute coronary syndrome patients, (CDIP Ref. 2019-012 CT#25891).
Intellectual Property disclosures:
2. Hardikar AA, Ranjan AK and Joglekar MV (2019) A circulating mRNA signature of endothelial damage in diabetes.
1. Joglekar MV and Hardikar AA (2019) Regulatory microRNAs offering immunomodulatory effect.
122. Scott ES, Januszewski AS, Carroll LM, Fulcher GR, Joglekar MV, Hardikar AA, Jones TW, Davis EA, Jenkins AJ (2021) Continuous subcutaneous insulin infusion alters microRNA expression and glycaemic variability in children with type 1 diabetes. Sci Rep. 17;11(1):16656. doi: 10.1038/s41598-021-95824-8. PMID: 34404828 121. Januszewski AS*, Cho YH*, Joglekar MV*, Farr RJ, Scott ES, Wong WKM, Carroll LM, Loh YW, Benitez-Aguirre PZ, Keech AC, O'Neal DN, Craig ME, Hardikar AA^, Donaghue KC^, Jenkins AJ^ (2021) Insulin micro-secretion in Type 1 diabetes and related microRNA profiles. Sci Rep. 11(1):11727. doi: 10.1038/s41598-021-90856-6. PMID: 34083567 (*equal first authors, ^equal senior authors) 120. Joglekar MV, Dong CX, Wong WKM, Dalgaard LT and Hardikar AA (2021) A birds' eye view of the dynamics of pancreatic beta-cell heterogeneity. Acta Physiologica. e13664. doi: 10.1111/apha.13664. PMID: 33884752
119. Wong WKMW*, Joglekar MV*, Saini V, Jiang G, Dong CX, Chaitarvornkit A, Maciag GJ, Gerace D, Farr RJ, Satoor SN, Sahu S, Sharangdhar T, Ahmed AS, Chew Y, Liuwantara D, Heng B, Lim CK, Hunter J, Januszewski AS, Sørensen AE, Akil AS, Gamble JR, Loudovaris T, Kay TW, Thomas HE, O’Connell PJ, Guillemin GJ, Martin D, Simpson AM, Hawthorne WJ, Dalgaard LT, Ma RCW and Hardikar AA (2021) Machine learning workflows identify a microRNA signature of insulin transcription in human tissues (*equal first authors) iScience. 24(4):102379. doi: 10.1016/j.isci.2021.102379 PMID: 33981968 118. Shihana F, Wong WKM, Joglekar MV, Mohamed F, Gawarammana IB, Isbister GK, Hardikar AA*, Seth D*, Buckley N* (2021) Urinary microRNAs as non-invasive biomarkers for toxic acute kidney injury in humans. (*equal senior authors) Sci Rep. 11(1):9165. doi: 10.1038/s41598-021-87918-0. PMID: 33911095 117. Joglekar MV, Wong WKM, Khan F, Georgiou HM, Shub A, Hardikar AA*, Lappas M,* (2021) Post-partum circulating microRNA enhance prediction of future type 2 diabetes in women with previous gestational diabetes (*: equal senior/corresponding authors). Diabetologia. 64(7):1516-1526. doi: 10.1007/s00125-021-05429-z. PMID: 33755745 116.Cheng F, Luk AO, Wu H, Kp Lim C, Carroll L, Ht Tam C, Fan B, Yang A, Sh Lau E, Cw Ng A, Man Lee H, Chow E, Kong AP, Keech AC, V Joglekar M, Yee So W, Jenkins AJ, Cn Chan J, Hardikar AA, Cw Ma R (2021) Shortened Relative Leukocyte Telomere Length is Associated with All-cause Mortality in Type 2 Diabetes- Analysis from the Hong Kong Diabetes Register. Diabetes Res Clin Pract. Jan 7:108649. doi:10.1016/ j.diabres. 2021.108649. Online ahead of print. PMID: 33422583 115. Joglekar MV, Patil RR, Satoor SN, Wong WKM, Karandikar MS, and Hardikar AA, (2021) Promoting pro-endocrine differentiation and graft maturation following surgical resection of the mouse pancreas (accepted for publication on September 08, 2019) Meth. Mol Biol. 114. Cheng F, Carroll L, Joglekar MV, Januszewski A, Wong KK, Hardikar AA*, Jenkins AJ*, Ma RCW* (2020) Diabetes, metabolic disease and telomere length (Accepted for publication October 08, 2020; *: equal senior/corresponding authors). The Lancet D&E Nov 26:S2213-8587(20)30365-X. doi: 10.1016/S2213-8587(20)30365-X. Online ahead of print. PMID: 33248477 2020 (Moved group from Sydney University to Western Sydney University, Australia) 113. Shihana F, Mohamed F, Joglekar MV, Hardikar AA, Seth D, Buckley NA (2020) Urinary versus serum microRNAs in human oxalic acid poisoning: contrasting signals and performance (Accepted for publication September 03, 2020). Toxicology Letters Nov 1;334:21-26. doi: 10.1016/j.toxlet.2020.09.003. Epub 2020 Sep 7. PMID: 32910981 112. Gamage HKAM, Chong RWW, Bucio-Noble D, Kautto L, Hardikar AA, Balld MS, Molloy MP, Packer NH, Paulsen IT (2020) Changes in dietary fibre intake in mice reveal associations between colonic mucin O-glycosylation and specific gut bacteria (Accepted for publication). Gut Microbes. Nov 9;12(1):1802209. doi: 10.1080/19490976.2020.1802209. PMID: 32991816 111. Cheng F, Luk AO, Tam CHT, Fan B, Wu H, Yang A, Lau ESH, Ng ACW, Lim CKP, Lee HM, Chow E, Kong AP, Keech AC, Joglekar MV, So WY, Jenkins A, Chan JCN, Hardikar AA and Ma RCW (2020) Shortened Relative Leukocyte Telomere Length is Associated with Prevalent and Incident Cardiovascular Complications in Type 2 Diabetes- Analysis from the Hong Kong Diabetes Register (Jul 13:dc200028. doi: 10.2337/dc20-0028. Online ahead of print. PMID: 32661111). Diabetes Care Sep;43(9):2257-2265. doi: 10.2337/dc20-0028. Epub 2020 Jul 13. PMID: 32661111 110. Joglekar MV, Satoor SN, Wong WKM, Cheng F, Ma RCW, Hardikar AA. (2020) An Optimised Step-by-Step Protocol for Measuring Relative Telomere Length. Methods Protoc. 2020 Apr 3;3(2):E27. doi: 10.3390/mps3020027. PMID: 32260112 109. Williams MD, Joglekar MV, Hardikar AA and Wong WKM (2020) Directed differentiation into insulin-producing cells using microRNA manipulation; 15: 1-4 (commentary) Open Medicine Jun 19;15(1):567-570. doi: 10.1515/med-2020-0170. eCollection 2020. PMID: 33336012 108. Barraclough JY, Joglekar MV, Januszewski AS, Martínez G, Celermajer DS, Keech AC, Hardikar AA and Patel S. (2020) A MicroRNA Signature in Acute Coronary Syndrome Patients and Modulation by Colchicine. J Cardiovasc Pharmacol Ther. 2020 May 1:1074248420922793. doi: 10.1177/1074248420922793. Online ahead of print. PMID: 32356454 107. Shihana F, Joglekar MV, Raubenheimer J, Hardikar AA, Buckley NA, Seth D (2020) Circulating human microRNA biomarkers of oxalic acid induced acute kidney injury Arch Toxicol. 94(5):1725-1737. doi: 10.1007/s00204-020-02679-5. PMID: 32086547 ------------------------------------------------------------------------------------------------------------------------------------------------------------------ 2019 106. Scott ES, McGrath RT, Januszewski AS, Calandro D, Hardikar AA, O’Neal DN, Fulcher GR, Jenkins AJ (2019) HbA1c Variability in Adults With Type 1 Diabetes on Continuous Subcutaneous Insulin Infusion (CSII) Therapy Compared To Multiple Daily Injection (MDI) Treatment (accepted for publication on December 02, 2019) BMJ Open 9(12):e033059. doi: 10.1136/bmjopen-2019-033059. PMID: 31888933
105. Barraclough J, Joan M, Joglekar M, Hardikar A and Patel S (2019) Prognostic utility of microRNAs in patients with acute coronary syndromes– A systematic review. Cells : 8(12):1572. doi: 10.3390/cells8121572.
104. Sørensen AE, Udesen PB, Maciag G, Geiger J, Saliani N, Januszewski A, Jiang G, Ma RC, Hardikar AA, Wissing MLM, Englund ALM and Dalgaard LT (2019) Hyperandrogenism and metabolic syndrome is associated with changes in serum-derived microRNAs in women with polycystic ovary syndrome (accepted for publication on October 14, 2019) Frontiers in Medicine (Translational Medicine) ;6:242. doi: 10.3389/fmed.2019.00242. eCollection 2019. PMID: 31737638
103. Bensellam M, Chan JY, Lee KL, Joglekar M, Hardikar A, Loudovaris T, Thomas H, Jonas JC, and Laybutt DR (2019) Phlda3 regulates beta-cell survival during stress. Scientific Reports 6;9(1):12827. doi: 10.1038/s41598-019-49289-5.
102. Wong WKM, Jiang G, Sørensen AE, Chew YV, Maynard CL, Liuwantara D, Williams L, O’Connell P, Dalgaard LT, Ma RC, Hawthorne WJ, Joglekar MV, and HardikarAA (2019) The long noncoding RNA MALAT1 predicts human pancreatic islet isolation quality; JCI insight pii: 129299. doi: 10.1172/jci.insight.129299. PMID: 31361602
101. Lappas M,Georgiou HM, Willcox J, Permezel M, Shub A, Maynard CL, Joglekar MV, Hardikar AA (2019) Postpartum circulating cell-free insulin DNA levels are higher in women with previous gestational diabetes mellitus who develop type 2 diabetes in later life. J Diabetes Res. 3264184. doi: 10.1155/2019/3264184..
100. Kim SY, Joglekar MV, Hardikar AA, Phan TH, Khanal D, Tharkar P, Limantoro C, Johnson J, Kalionis B and Chrzanowski W (2019) Placenta stem/stromal cell-derived extracellular vesicles for the treatment of lung diseases. Proteomics ; 19(17): e1800166. doi: 10.1002/pmic.201800166.
99. Udesen PB, Sørensen AE, JoglekarMV, Hardikar AA, Wissing MM, Englund AM, Dalgaard LT (2019) Levels of circulating insulin cell-free DNA in women with Polycystic Ovary Syndrome – a longitudinal cohort study. Rep Biol. Endocrinol 17(1):34. doi: 10.1186/s12958-019-0478-7.
98. Farr RJ, Wong WKM, Maynard C, Tersey SA, Mirmira RG, Hardikar AA and Joglekar MV (2019) Comparative analysis of diagnostic platforms for measurement of unmethylated / methylated insulin DNA. J Biol Meth 6(2). pii: e113. doi: 10.14440/jbm.2019.280.
97. Poddar A, Joglekar MV, Hardikar AA and Shukla R (2019) A novel gene delivery approach using metal organic frameworks in human islet-derived cells Meth. Mol. Biol; 2029:81-91. doi: 10.1007/978-1-4939-9631-5_7, PMID: 31273735.
96. Maynard CL, Wong WKM, Hardikar AA and Joglekar MV (2019) Droplet digital PCR for measuring absolute copies of gene transcripts in human islet-derived progenitor Cells Meth. Mol. Biol; 2029:37-48. doi: 10.1007/978-1-4939-9631-5_4, PMID: 31273732.
95. Slykerman R, Joglekar M, Hardikar A, Satoor S, Thompson JM, Jenkins AJ, Mitchell EA, Murphy R (2019) Maternal stress during pregnancy and small for gestational age birthweight are not associated with telomere length at 11 years of age. Gene 694:97-101. doi: 10.1016/j.gene.2019.01.017. Epub 2019 Feb 7.
94. Williams MD, Joglekar MV, Satoor SN, Wong WKM, Keramidaris E, Rixon A, O’Connell P, Hawthorne WJ, Mitchell GM and Hardikar AA (2019) Epigenetic and transcriptome profiling identifies a population of visceral adipose-derived progenitor cells with potential to differentiate into endocrine pancreatic lineage; Cell Transplantation 28(1):89-104. doi: 10.1177/0963689718808472. Epub 2018 Oct 30, PMID: 30376726. 2018 93. Joglekar MV, Sorensen A, Wong KM, Hardikar AA, Dalgaard LT (2018) Non-coding RNAs in islet β-cell maturation and development; Noncoding RNA 4(4). pii: E41. doi: 10.3390/ncrna4040041..
92. Joglekar MV, Wong WKM, Maynard C, Umrani MR, Martin D, Loudovaris T, Thomas HE, Dalgaard LT and Hardikar AA (2018) Expression of miR-206 in human islets and its role in glucokinase regulation. Am J Physiol - Endocrinol & Metab;315(4):E634-E637. doi: 10.1152/ajpendo.00152.2018 2017 91. Hakami NY, Ranjan AK, Hardikar AA, Dusting GJ, Peshavariya HM (2017) Role of NADPH Oxidase-4 in Human Endothelial Progenitor Cells. Frontiers in Physiology. 23;8:150. 90. Umrani MR, Joglekar MV, Somerville Glover E, Wong W and Hardikar AA (2017) Connexins and microRNAs: interlinked players in regulating islet function? Islets; 3;9(5):99-108 2016 89. Joglekar MV, Trivedi PM, Kay TW, Hawthorne WJ, O'Connell PJ, Jenkins AJ, Hardikar AA, Thomas HE. (2016) Human islet cells are killed by BID-independent mechanisms in response to FAS ligand Apoptosis; 21(4):379-89. doi: 10.1007/s10495-016-1212-y.PMID: 26758067
88. Joglekar MV, Januszewski AS, Jenkins AJ, Hardikar AA. (2016) Circulating microRNA Biomarkers of Diabetic Retinopathy. Diabetes. ;65(1):22-4. doi: 10.2337/dbi15-0028. PMID: 26696637 2015 87. Jenkins AJ, Joglekar MV, Hardikar AA, Keech AC, O'Neal DN, Januszewski AS (2015) Biomarkers in Diabetic Retinopathy. Rev. Diabet Studies; 12(1-2):159-95. doi: 10.1900/RDS.2015.12.159. Epub 2015 Aug 10.PMID: 26676667
86. Farr RJ, Joglekar MV, Hardikar AA.(2015) Circulating microRNAs in Diabetes Progression: Discovery, Validation, and Research Translation. EXS. 2015;106:215-44. doi: 10.1007/978-3-0348-0955-9_10. PMID: 26608206
85. Kim KW, Ho A, Alshabee-Akil A, Hardikar AA, Kay TW, Rawlinson WD, Craig ME.(2015) Coxsackievirus B5 Infection Induces Dysregulation of MicroRNAs Predicted to Target Known Type 1 Diabetes Risk Genes in Human Pancreatic Islets. Diabetes *. 2015 Nov 11. pii: db150956.
* Also special commentary in Nature Reviews - Endocrinology and Metabolism
84. Hardikar AA1,°, Satoor SN°, Karandikar MS°, Joglekar MV° et al.. (2015) Susceptibility to obesity and diabetes following multigeneration undernutrition is not reversed by two generations of nutrient availability. Cell Metabolism (PMID: 26166746); 1 AAH – First and corresponding author, ° equal contribution amongst 19 authors (Cover story).
83. Farr RJ, Januszewski AS, Joglekar MV, Liang H, McAulley AK, Hewitt AW, Thomas HE, Loudovaris T, Kay TW, Jenkins A, Hardikar AA (2015) A comparative analysis of high-throughput platforms for validation of a circulating microRNA signature in diabetic retinopathy. Scientific Reports. 2;5:10375. www.nature.com/srep; doi: 10.1038/srep10375.
82. Wong W, Farr RJ, Joglekar MV, Januszewski AS, Hardikar AA (press) Probe-based real-time PCR approaches for quantitative measurement of microRNAs. J Visual Exp 14;(98). doi: 10.3791/52586
81. Liu J, Joglekar MV, Sumer H, Hardikar AA, Teede H, Verma PJ (2015) Integration-Free Human Induced Pluripotent Stem Cells from Type 1 Diabetes Patient Skin Fibroblasts Show Upregulation of Pancreas-Specific microRNAs, Cell Medicine; 7(1): 15-24 2014 80. Hardikar AA, Farr RJ, Joglekar MV (2014) Circulating microRNAs: Understanding the limits for quantitative measurement by real-time PCR J Am Heart Assoc. 3(1): e000792. doi: 10.1161/JAHA.113.000792.
79. Williams MD, Wong W, Rixon A, Satoor SN, Hardikar AA, Joglekar MV. (2014) Pdx1 (GFP/w) mice for isolation, characterization, and differentiation of pancreatic progenitor cells. Meth. Mol. Biol, 1194:271-88. doi: 10.1007/978-1-4939-1215-5_15.
78. Satoor SN, Patil DP, Kristensen HD, Joglekar MV, Shouche Y, Hardikar AA. (2014) Manipulation and assessment of gut microbiome for metabolic studies. Meth. Mol. Biol 1194:449-69. doi: 10.1007/978-1-4939-1215-5_26. 2013 77. Hardikar AA: on behalf of the RAPID Study group (2013) microRNAs in Pancreatic Beta Cells: from Cradle to the Grave Pediatric Endocrinology Reviews ;11(1):14-20.
76. Sundrani DP, Reddy US, Joshi AA, Mehendale SS, Chavan-Gautam PM, Hardikar AA, Chandak GR, Joshi SR (2013) Differential placental methylation and expression of VEGF, FLT-1 and KDR genes in human term and preterm preeclampsia. Clinical Epigenetics. 26;5(1):6. doi: 10.1186/1868-7083-5-6.
75. Satoor SN and Hardikar AA (2013) Maternal nutrition, nutrient transfer & foetal pancreas development. Ind J Med Res.;137(2):249-50. 2012 (Moved group from Melbourne to Sydney University, Sydney, Australia) 74. Hardikar AA, Walker MD, Lynn F (2012) Non-codimng RNAs. Exp Diabetes Res. 629249. doi: 10.1155/2012/629249.
73. Ranjan AK, Joglekar MV, Atre AN, Patole M, Bhonde RR and Hardikar AA (2012) Simultaneous Imaging of microRNA / mRNA Territories with Protein Territory in Mammalian Cells at Single Cell Resolution. RNA Biology 9:7, 949-53. doi: 10.4161/rna.20484
72. Ranjan AK, Joglekar MV, Atre AN, Patole M, Bhonde RR and Hardikar AA (2012) Cellular detection of multiple antigens at single cell resolution using antibodies generated from the same species. J Imm Methods; 379(1-2):42-7. doi: 10.1016/ j.jim.2012.02.018
71. Joglekar MV and Hardikar AA (2012) Isolation, characterization and expansion of islet-derived progenitor cells. Meth. Mol. Biol 879:351-66. doi: 10.1007/978-1-61779-815-3_21.
70. Kumar U, Ranjan AK, Chandrashekhar S, Hardikar AA, Pundle A and Poddar P. (2012) Green approach towards size controlled synthesis of biocompatible antibacterial metal nanoparticles in aqueous phase using lysozyme. Current Nanoscience 8(1), 130-140(11) -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2011 69. Vaithilingam V, Quayum N, Joglekar MV, Jensen J, Hardikar AA, Oberholzer J, Guillemin GJ, PhD, Tuch BE (2011) Effect of alginate encapsulation on the cellular transcriptome of human islets. Biomaterials 32(33):8416-25
68. Satoor SN, Puranik AS, Kumar S, Williams MD, Ghale M, Rahalkar A, Karandikar MS, Shouche Y, Patole M, Bhonde RR, Yajnik CS and Hardikar AA (2011) Location, location, location: Beneficial effects of autologous fat transplantation. Scientific Reports 2011;1:81. (http://www.nature.com/srep/2011/110902/srep00081/full/srep00081.html)
67. Ansarullah, Bhavna Bharucha, Mitesh Dwivedi, Naresh C Laddha, Rasheedunnisa Begum, Hardikar AA and A V Ramachandran (2011) Antioxidant rich flavonoids from Oreocnide integrifolia enhance glucose uptake and insulin secretion and protects pancreatic beta-cells from streptozotocin insult. BMC Comp Alt Med 12;11:126. doi: 10.1186/1472-6882-11-126.
66. Ansarullah, Bhavna Bharucha, Malati Umarani, Mitesh Dwivedi, Naresh C Laddha, Rasheedunissa Begum, Hardikar AA, and Ramachandran A.V (2011) Oreocnide integrifolia flavonoids augment reprogramming for islet neogenesis and ß-cell regeneration in pancreatectomized BALB/c mice Evid-Based Complement Alternat Med 260467. doi: 10.1155/2012/260467.
65. Forster N, Penington A, Hardikar AA, Palmer J, Hussey A, Taj J, Morrison W, Feeney S (2011) A prevascularised tissue engineering chamber supports growth and function of islets and progenitor cells in diabetic mice, Islets 3(5):271-83.
64. Williams MD, Mitchell GM and Hardikar AA (2011) Stem cells: Epigenetic basis of differentiation Open Stem Cells 3:28-33
63. Phadnis SM, Joglekar MV, Dalvi1 MP, Muthyala S, Nair PD, Ghaskadbi SM, Bhonde RR and Hardikar AA (2011) Human bone marrow-derived mesenchymal cells differentiate and mature into endocrine pancreatic lineage in vivo. Cytotherapy 13(3): 279-293 Cover story
62. Ansarullah, Jayaraman S, Hardikar AA and Ramachandran AV (2011) Influence of Oreocnide integrifolia (Gaud.) Miq on IRS-1, Akt and Glut-4 in Fat-Fed C57BL/6J Type 2 Diabetes Mouse Model. Evid-Based Complement Alternat Med 13 (3): 1-9 doi:10.1093/ecam/neq014. 2010 61. Parekh VS, Umrani MR and Hardikar AA (2010) Taurine supports preservation of pro-endocrine cell types in human umbilical cord blood-derived mononuclear cells during cryostorage. Transplant Proc, 42(10):4619-21
60. Joglekar MV and Hardikar AA (2010) Epithelial-to-mesenchymal transition in pancreatic islet beta cells. Cell Cycle 15;9(20):4077-9
59. Chayosumrit M, Hardikar AA and Sidhu K. Role of the Glucagon-like Peptide-1 Receptor Agonist in Maintaining Pluripotency in Human Embryonic Stem Cells. Open Stem Cells 2011; 3: 11-22
58. Joglekar MV, Wei CJ and Hardikar AA (2010) Quantitative estimation of multiple microRNAs and mRNAs from a single cell. Cold Spring Harb. Protocols 1;2010(8):pdb.prot5478. doi: 10.1101/pdb.prot5478 Cover story
57. Wu Y, Li J, Saleem S, Yee S, Hardikar AA, and Wang R (2010) C-Kit and stem cell factor regulate PANC-1 cell differentiation to insulin- and glucagon-producing cells. Lab Investigation 90(9):1373-84
56. Khandwekar AP, Patil DP, Hardikar AA, Shouche YS, Doble M. (2010) In vivo modulation of foreign body response on polyurethane by surface entrapment technique. J Biomed Mater Res. 95(2):413-23
55. Sasikala M, Swapna G, Pavan K, Rao GV, Hardikar AA and Reddy DN (2010) Reduced expression of pdx-1 correlates with decreased beta cell function in chronic pancreatitis. Pancreas 39(6):856-62
54. Lee J, Jo J, Hardikar AA, Periwal V and Rane SG (2010) Cdk4 regulates recruitment of quiescent β-cells and ductal epithelial progenitors to reconstitute β-cell mass PLoS ONE 13;5(1):e8653 2009 (Moved group from Pune, India to Melbourne, Australia) 53. Phadnis SM, Ghaskadbi SM, Hardikar AA, Bhonde RR (2009) Mesenchymal stem cells derived from bone marrow of diabetic patients portrait unique markers influenced by the diabetic microenvironment. Rev Diabet Stud. 6(4):260-70.
52. Ranjan AK, Kumar U, Hardikar AA, Poddar P, Nair PD, Hardikar AA (2009) Human blood vessel-derived endothelial progenitors for endothelialization of small diameter vascular prosthesis. PLoS ONE 4(11):e7718.PMID: 19890388
51. Joglekar MV, Patil D, Joglekar VM, Rao GV, Reddy DN, Sasikala M, Shouche Y and Hardikar AA (2009) The miR-30 Family microRNAs Confer Epithelial Phenotype to Human Pancreatic Cells. Islets 1(2): 137 - 147. Cover story
50. Parekh VS, Joglekar MV and Hardikar AA (2009) Differentiation of human umbilical cord blood derived mononuclear cells to endocrine pancreatic lineage. Differentiation 78(4):232-40. Cover story
49. Joglekar MV, Joglekar VM, Joglekar SV and Hardikar AA (2009), Human fetal pancreatic insulin-producing cells proliferate in vitro. J. Endocrinology 201(1):27-36, Epub 2009 May 6 Cover story
48. Sahu S*, Joglekar MV*, Dumbre R, Phadnis SM, Tosh D and Hardikar AA, (2009) Islet-like cell clusters occur naturally in human gall bladder and are retained in diabetic conditions J Cell Mol Med: 13(5):999-1000; *: equal first authors.
47. Joglekar MV, Joglekar VM and Hardikar AA (2009) Expression of islet-specific microRNAs during human pancreatic development. Gene Exp Patterns; 9(2): 109-113.
46. Dalvi MP, Umrani MR, Joglekar MV, Hardikar AA (2009) Human pancreatic islet progenitor cells demonstrate phenotypic plasticity in vitro. J Biosci. 34(4):523-8.
45. Ranjan AK, Joglekar MV and Hardikar AA (2009) Endothelial cells in pancreatic islet development and function Islets 1(1); 2 – 9
44. Kode JA, Mukherjee S, Joglekar MV and Hardikar AA (2009) Mesenchymal Stem cells: Immunobiology and role in immunomodulation and tissue regeneration. Cytotherapy : 11(4):377-91 2007 43. Joglekar MV, Parekh VS, Mehta S, Bhonde RR and Hardikar AA (2007) MicroRNA Profiling of Developing and Regenerating Pancreas Reveal Post-transcriptional Regulation of Neurogenin3. Developmental Biology 311(2): 603-612
42. Joglekar MV, Parekh VS and Hardikar AA (2007) New Pancreas from Old: Microregulators of Pancreas Regeneration Trends Endocrinol Metab 18(10):393-400. Cover citation. 2006 41. Phadnis SM*, Joglekar MV*, Venkateshan V, Ghaskadbi SM, Hardikar AA, Bhonde RR. (2006) Human umbilical cord blood serum promotes growth, proliferation, as well as differentiation of human bone marrow-derived progenitor cells. In Vitro Cell Dev Biol . 42(10):283-6.
40. Hardikar AA, Lees JG, Sidhu KS, Colvin E and Tuch BE; Stem-Cell Therapy for Diabetes Cure: How Close Are We? (2006) Current Stem Cell Research and Therapy: 1:425-436 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2005 and before establishing this group (post-doctoral training AAH) 39. Gershengorn MC, Geras-Raaka E, Hardikar AA, Raaka BM. (2005) Are better islet cell precursors generated by epithelial-to-mesenchymal transition? Cell Cycle. 4:380-382.
38. Gershengorn MC, Hardikar AA, Wei C, Geras-Raaka E, Marcus-Samuels B, Raaka BM (2004) Epithelial-to-Mesenchymal Transition Generates Proliferative Human Islet Precursor Cells. Science 306:2261-2264.
37. Hardikar AA (2004) Pancreas regeneration: Generating new pancreas from old. Trends Endocrinol Metab. 15:198-203 Cover story
36. Hardikar AA, Marcus-Samuels B, Geras-Raaka E, Raaka BM, Gershengorn MC (2003) Human pancreatic precursor cells secrete FGF2 to stimulate clustering into hormone-expressing islet-like cell aggregates. Proc Natl Acad Sci U S A. 100(12): 7117-7122.
35. Hardikar AA, Wang XY, Williams LJ, Kwok J, Wong R, Yao M, Tuch BE. (2002) Functional maturation of fetal porcine beta-cells by glucagon-like peptide 1 and cholecystokinin. Endocrinology; 143:3505-3514.
34. Merezek S, Hardikar AA, Yajnik CS, Remacle C and Reusens B (2001) Intra-uterine protein malnutrition and diabetes: the role of sulphur amino acids. J Endocrinol; 171:299-308.
33. Hardikar AA, Risbud MV, Remacle C, Reusens B, Hoet JJ, Bhonde RR. (2001) Islet cryopreservation: improved recovery following taurine pretreatment. Cell Transplant; 10:247-253.
32. Hardikar AA, Nath BB. (2001) Chromosomal polymorphism is associated with nematode parasitism in a natural population of a tropical midge. Chromosoma; 110: 58-64.
31. Risbud MV, Hardikar AA, Bhat SV, Bhonde RR. (2000) pH-sensitive freeze-dried chitosan-polyvinyl pyrrolidone hydrogels as controlled release system for antibiotic delivery. J Control Release; 68: 23-30.
30. Hardikar AA, Risbud MV, Bhonde RR. (2000) Improved post-cryopreservation recovery following encapsulation of islets in chitosan-alginate microcapsules. Transplant Proc; 32: 824-5.
29. Risbud M, Hardikar A, Bhonde R. (2000) Growth modulation of fibroblasts by chitosan-polyvinyl pyrrolidone hydrogel: implications for wound management? J Biosci ; 25: 25-31.
28. Risbud M, Hardikar A, Bhonde R. (2000) Chitosan-polyvinyl pyrrolidone hydrogels as candidate for islet immunoisolation: in vitro biocompatibility evaluation. Cell Transplant; 9 : 25-31.
27. Hardikar AA, Bhonde RR. (1999) Modulating experimental diabetes by treatment with cytosolic extract from the regenerating pancreas. Diabetes Res Clin Pract; 46: 203-11.
26. Hardikar AA, Karandikar MS, Bhonde RR. (1999) Effect of partial pancreatectomy on diabetic status in BALB/c mice. J Endocrinol ; 162: 189-195.
25. Hardikar AA, Risbud MV and Bhonde RR (1999) A simple microcapsule generator design for islet encapsulation, J. Biosci. 24 (3): 371 - 376. Editorial /commentaries:
24. McGowan EM, Simpson A, McManaman J, Boonyaratanakornkit V, Hardikar AA (2015) Hijacking of Endocrine and Metabolic Regulation in Cancer and Diabetes. Biomed Res Int.:386203. doi: 10.1155/2015/386203. Epub 2015 Jul 9.
23. Hardikar AA, Walker M, Lynn FC (2013) Non-coding RNAs (Editorial) J Diabetes Res. (2012)
22. Hardikar A (2013) microRNAs: small regulators of human disease. Non-codingRNAs in Endocrinology
21. Satoor SN and Hardikar AA (2013) Maternal nutrition, nutrient transfer and foetalpancreas development. Invited commentary in press In J Med Res
20. Joglekar MV, Parekh VS and Hardikar AA (2011) microRNAs in endocrine pancreas development, differentiation and disease. In J Exp. Biol. (invited article in press)
19. Hardikar AA and Tosh D (2009) Commentary: β-cells in the lab. Nature India, doi 10:1038/nindia.2009.160 (http://www.nature.com/nindia/2009/090625/full/nindia.2009.160.html)
18. Sahu S, Tosh D and Hardikar AA (2009) Commentary: New sources of beta-cells for treating diabetes. J. Endocrinology: 202(1):13-6
17. Hardikar A, (2004) Role of Incretins in Pancreas Growth and Development (Editorial) J Pancreas 5(6):454-456.
Chapters in books:
16. Sahu S, Joglekar M, Yang S and Hardikar AA (2011) Gallbladder-derived islet stem cells, In "Stem Cells", ISBN: 978-953-307-412-2. Open Access Publishers, Vienna, Austria.
15. Joglekar MV and Hardikar AA (2013) Human fetal pancreatic progenitor cells in: Clinical issues of fetal tissue transplantation in medicine. Chapter 18, pp 237-249. Editor: Phillip Stubblefield and Niranjan Bhattacharya. Publisher: Springer
14. Lie D, Chayosumrit M, Hardikar A and Sidhu K (2010) Puluripotent stem cells and diabetes: Basic Science to Clinical Applications in: Frontiers in pluripotent stem cells research: Bench-to-Bedside Publisher: Betham Press, Editor: K Sidhu
13. Joglekar MV, Ranjan AK and Hardikar AA (2009) Pancreas development and regeneration. “In Stem cells: Organogenesis and Cancer” Editor: Dr. SR Singh, Book Editor & Managing Editor: Research Signpost/ Transworld Research Network press (http://www.ressign.com/). Frontiers in Bioscience, NIH, USA
12. Hardikar AA and Gershengorn MC (2003) Chapter 51: ‘Stem Cells’ in 3rd edition of ‘Diabetes Mellitus: A Fundamental and Clinical Text’, edited by: Dr. Derek LeRoith, Simeon I. Taylor and Jerrold M. Olefsky.
11. Shukla R, Risbud MR, Hardikar AA, Bhonde RR, (2004) Chitosan and chitin derivatives in islet immunoisolation and transplantation. In “Chitin and Chitosan: Opportunities and Challenges” Chapter 15, p 211-222, eds; Dutta PK
10. Wong W, Hardikar AA and Joglekar MV (2017) Generation of human islet progenitor cells via epithelial to mesenchymal transition, in Pancreatic Islet Biology, Springer Humana press, eds Hardikar A, pp217-240.Books:
9. “Pancreatic Islet Biology” (2016). Chief Editor: Hardikar AA, Publisher: Springer press, USA, ISSN 2196-8985, ISBN: 978-3-319-45305-7 (print version) / 978-3-319-45307-1. (e-book version). A textbook for diabetes researchers with 12 chapters from 45 authors over 336 pages of text.
8. “Methods in Molecular Biology: Progenitor Cells” (2019) Co-editor with Chief Editor Dr. Mugdha Joglekar, University of Sydney for a book in the well-known Methods in Molecular Biology book series published by Springer Press, USA. Resources:
7. Wong W, Joglekar MV, Chew Y, Hawthorne WJ, Hardikar AA (2019) Human islets of varying quality: the good, the (not so) bad and the ugly; This collection represents whole transcriptome datasets for human islets that were stratified to high quality (Group 1), intermediary quality (Group 2) and poor quality (Group 3) islets (Wong WKM et al JCI Insight 2019). Series Accession: GSE134068ID: 200134068. Intellectual Property (filed)
6. Hardikar AA, Joglekar MV and Januszewski AS (2017) Intracellular microRNA Signatures of Insulin Production: WO2019000017 A1.
5. Hardikar AA, Joglekar MV and Januszewski AS (2017) Circulating microRNA signatures of islet beta cell death and progression to diabetes: WO2019000015 A1.
4. Hardikar AA, Wong W, Joglekar MV and Hawthorne WJ (2019) A long non-coding RNA that predicts islet isolation outcome (IP Australia # 2019202308).
3. Patel S, Hardikar A, Barraclough J and Keech AC: A miRNA signature to assess treatment efficacy in acute coronary syndrome patients, (CDIP Ref. 2019-012 CT#25891).
Intellectual Property disclosures:
2. Hardikar AA, Ranjan AK and Joglekar MV (2019) A circulating mRNA signature of endothelial damage in diabetes.
1. Joglekar MV and Hardikar AA (2019) Regulatory microRNAs offering immunomodulatory effect.