Peer reviewed publications
92. Lappas M,Georgiou HM, Willcox J, Permezel M, Shub A, Maynard CL, Joglekar MV, Hardikar AA (2019) Postpartum circulating cell-free insulin DNA levels are higher in women with previous gestational diabetes mellitus who develop type 2 diabetes in later life. J Diabetes Res (accepted for publication July 05, 2019).
91. Kim SY, Joglekar MV, Hardikar AA, Phan TH, Khanal D, Tharkar P, Limantoro C, Johnson J, Kalionis B and Chrzanowski W (2019) Placenta stem/stromal cell-derived extracellular vesicles for the treatment of lung diseases. Proteomics (accepted for publication July 02, 2019)
90. Udesen PB, Sørensen AE, JoglekarMV, Hardikar AA, Wissing MM, Englund AM, Dalgaard LT (2019) Levels of circulating insulin cell-free DNA in women with Polycystic Ovary Syndrome – a longitudinal cohort study. Rep Biol Endocrinol 17(1):34. doi: 10.1186/s12958-019-0478-7.
89. Farr RJ, Wong WKM, Maynard C, Tersey SA, Mirmira RG, Hardikar AA and Joglekar MV (2019) Comparative analysis of diagnostic platforms for measurement of unmethylated / methylated insulin DNA. J Biol Meth (in press).
88. Poddar A, Joglekar MV, Hardikar AA and Shukla R (2019) A novel gene delivery approach using metal organic frameworks in human islet-derived cells Methods Mol Biol .(in press).
87. Maynard CL, Wong WKM, Hardikar AA and Joglekar MV (2019) Droplet digital PCR for measuring absolute copies of gene transcripts in human islet-derived progenitor Cells Methods Mol Biol .(in press).
86. Slykerman R, Joglekar M, Hardikar A Satoor S, Thompson JM, Jenkins AJ, Mitchell EA, Murphy R (2019) Maternal stress during pregnancy and small for gestational age birthweight are not associated with telomere length at 11 years of age. Gene 694:97-101. doi: 10.1016/j.gene.2019.01.017. Epub 2019 Feb 7.
85. Williams MD, Joglekar MV, Satoor SN, Wong WKM, Keramidaris E, Rixon A, O’Connell P, Hawthorne WJ, Mitchell GM and Hardikar AA (2018) Epigenetic and transcriptome profiling identifies a population of visceral adipose-derived progenitor cells with potential to differentiate into endocrine pancreatic lineage; Cell Transplantation 28(1):89-104. doi: 10.1177/0963689718808472. Epub 2018 Oct 30.
84. Joglekar MV, Sorensen A, Wong KM, Hardikar AA, Dalgaard LT (2018) Non-coding RNAs in islet β-cell maturation and development; Noncoding RNA 4(4). pii: E41. doi: 10.3390/ncrna4040041..
83. Joglekar MV, Wong WKM, Maynard C, Umrani MR, Martin D, Loudovaris T, Thomas HE, Dalgaard LT and Hardikar AA (2018) Expression of miR-206 in human islets and its role in glucokinase regulation. Am J Physiol – Endocrinol Metab.;315(4):E634-E637. doi: 10.1152/ajpendo.00152.2018 82. Hakami NY, Ranjan AK, Hardikar AA, Dusting GJ, Peshavariya HM (2017) Role of NADPH Oxidase-4 in Human Endothelial Progenitor Cells. Frontiers Physiol. 23;8:150. 81. Umrani MR, Joglekar MV, Somerville Glover E, Wong W and Hardikar AA (2017) Connexins and microRNAs: interlinked players in regulating islet function? Islets; 3;9(5):99-108
80. Joglekar MV, Trivedi PM, Kay TW, Hawthorne WJ, O'Connell PJ, Jenkins AJ, Hardikar AA, Thomas HE. (2016) Human islet cells are killed by BID-independent mechanisms in response to FAS ligand Apoptosis; 21(4):379-89. doi: 10.1007/s10495-016-1212-y.PMID: 26758067
79. Joglekar MV, Januszewski AS, Jenkins AJ, Hardikar AA. (2016) Circulating microRNA Biomarkers of Diabetic Retinopathy.Diabetes.;65(1):22-4. doi: 10.2337/dbi15-0028. PMID: 26696637
78. Jenkins AJ, Joglekar MV, Hardikar AA, Keech AC, O'Neal DN, Januszewski AS (2015) Biomarkers in Diabetic Retinopathy. Rev Diabet Stud. Spring-Summer;12(1-2):159-95. doi: 10.1900/RDS.2015.12.159. Epub 2015 Aug 10.PMID: 26676667
77. Farr RJ, Joglekar MV, Hardikar AA.(2015) Circulating microRNAs in Diabetes Progression: Discovery, Validation, and Research Translation. EXS. 2015;106:215-44. doi: 10.1007/978-3-0348-0955-9_10. PMID: 26608206
76. Kim KW, Ho A, Alshabee-Akil A, Hardikar AA, Kay TW, Rawlinson WD, Craig ME.(2015) Coxsackievirus B5 Infection Induces Dysregulation of MicroRNAs Predicted to Target Known Type 1 Diabetes Risk Genes in Human Pancreatic Islets. Diabetes*. 2015 Nov 11. pii: db150956.
*Also special commentary in Nature Reviews - Endocrinol & Metab
75. Hardikar AA1,°, Satoor SN°, Karandikar MS°, Joglekar MV° et al.. (2015) Susceptibility to obesity and diabetes following multigeneration undernutrition is not reversed by two generations of nutrient availability. Cell Metabolism (PMID: 26166746); 1 AAH – First and corresponding author, ° equal contribution amongst 19 authors (Cover story).
74. Farr RJ, Januszewski AS, Joglekar MV, Liang H, McAulley AK, Hewitt AW, Thomas HE, Loudovaris T, Kay TW, Jenkins A, Hardikar AA (2015) A comparative analysis of high-throughput platforms for validation of a circulating microRNA signature in diabetic retinopathy. Sci Rep 2;5:10375. www.nature.com/srep; doi: 10.1038/srep10375.
73. Wong W, Farr RJ, Joglekar MV, Januszewski AS, Hardikar AA (press) Probe-based real-time PCR approaches for quantitative measurement of microRNAs. J Vis Exp 14;(98). doi: 10.3791/52586
72. Liu J, Joglekar MV, Sumer H, Hardikar AA, Teede H, Verma PJ (2015) Integration-Free Human Induced Pluripotent Stem Cells from Type 1 Diabetes Patient Skin Fibroblasts Show Upregulation of Pancreas-Specific microRNAs, Cell Medicine; 7(1): 15-24
71. Hardikar AA, Farr RJ, Joglekar MV (2014) Circulating microRNAs: Understanding the limits for quantitative measurement by real-time PCR J Am Heart Assoc. 3(1): e000792. doi: 10.1161/JAHA.113.000792.
70. Williams MD, Wong W, Rixon A, Satoor SN, Hardikar AA, Joglekar MV. (2014) Pdx1 (GFP/w) mice for isolation, characterization, and differentiation of pancreatic progenitor cells. Methods Mol Biol , 1194:271-88. doi: 10.1007/978-1-4939-1215-5_15.
69. Satoor SN, Patil DP, Kristensen HD, Joglekar MV, Shouche Y, Hardikar AA. (2014) Manipulation and assessment of gut microbiome for metabolic studies. Methods Mol Biol 1194:449-69. doi: 10.1007/978-1-4939-1215-5_26.
68. Hardikar AA: on behalf of the RAPID Study group (2013) microRNAs in Pancreatic Beta Cells: from Cradle to the Grave Pediatric Endocrinology Reviews; 11(1):14-20.
67. Sundrani DP, Reddy US, Joshi AA, Mehendale SS, Chavan-Gautam PM, Hardikar AA, Chandak GR, Joshi SR (2013) Differential placental methylation and expression of VEGF, FLT-1 and KDR genes in human term and preterm preeclampsia. Clinical Epigenetics. 26;5(1):6. doi: 10.1186/1868-7083-5-6.
66. Satoor SN and Hardikar AA (2013) Maternal nutrition, nutrient transfer & foetal pancreas development. In J Med Res.;137(2):249-50.
65. Hardikar AA, Walker MD, Lynn F (2012) Non-codimng RNAs. Exp Diabetes Res. 629249. doi: 10.1155/2012/629249.
64. Ranjan AK, Joglekar MV, Atre AN, Patole M, Bhonde RR and Hardikar AA (2012) Simultaneous Imaging of microRNA / mRNA Territories with Protein Territory in Mammalian Cells at Single Cell Resolution. RNA Biology 9:7, 949-53. doi: 10.4161/rna.20484
63. Ranjan AK, Joglekar MV, Atre AN, Patole M, Bhonde RR and Hardikar AA (2012) Cellular detection of multiple antigens at single cell resolution using antibodies generated from the same species. J Immunol Methods 379(1-2):42-7. doi: 10.1016/j.jim.2012.02.018. Epub 2012 Mar 4.
62. Joglekar MV and Hardikar AA (2012) Isolation, characterization and expansion of islet-derived progenitor cells. Methods Mol Biol 879:351-66. doi: 10.1007/978-1-61779-815-3_21.
61. Kumar U, Ranjan AK, Chandrashekhar S, Hardikar AA, Pundle A and Poddar P. (2012) Green approach towards size controlled synthesis of biocompatible antibacterial metal nanoparticles in aqueous phase using lysozyme. Current Nanoscience 8(1), 130-140(11)
60. Vaithilingam V, Quayum N, Joglekar MV, Jensen J, Hardikar AA, Oberholzer J, Guillemin GJ, PhD, Tuch BE (2011) Effect of alginate encapsulation on the cellular transcriptome of human islets. Biomaterials 32(33):8416-25
59. Satoor SN, Puranik AS, Kumar S, Williams MD, Ghale M, Rahalkar A, Karandikar MS, Shouche Y, Patole M, Bhonde RR, Yajnik CS and Hardikar AA (2011) Location, location, location: Beneficial effects of autologous fat transplantation. Sci Rep 2011;1:81. (http://www.nature.com/srep/2011/110902/srep00081/full/srep00081.html)
58. Ansarullah, Bhavna Bharucha, Mitesh Dwivedi, Naresh C Laddha, Rasheedunnisa Begum, Anandwardhan A Hardikar and A V Ramachandran (2011) Antioxidant rich flavonoids from Oreocnide integrifolia enhance glucose uptake and insulin secretion and protects pancreatic beta-cells from streptozotocin insult. BMC Comp Alt Med 12;11:126. doi: 10.1186/1472-6882-11-126.
57. Ansarullah, Bhavna Bharucha, Malati Umarani, Mitesh Dwivedi, Naresh C Laddha, Rasheedunissa Begum, Anandwardhan A Hardikar, and Ramachandran A.V (2011) Oreocnide integrifolia flavonoids augment reprogramming for islet neogenesis and ß-cell regeneration in pancreatectomized BALB/c mice Evid-Based Complement Alt Med 260467. doi: 10.1155/2012/260467.
56. Forster N, Penington A, Hardikar AA, Palmer J, Hussey A, Taj J, Morrison W, Feeney S (2011) A prevascularised tissue engineering chamber supports growth and function of islets and progenitor cells in diabetic mice, Islets 3(5):271-83.
55. Williams MD, Mitchell GM and Hardikar AA (2011) Stem cells: Epigenetic basis of differentiation Open Stem Cells 3:28-33
54. Phadnis SM, Joglekar MV, Dalvi1 MP, Muthyala S, Nair PD, Ghaskadbi SM, Bhonde RR and Hardikar AA (2011) Human bone marrow-derived mesenchymal cells differentiate and mature into endocrine pancreatic lineage in vivo. Cytotherapy 13(3): 279-293 Cover story
53. Ansarullah, Jayaraman S, Hardikar AA and Ramachandran AV (2011) Influence of Oreocnide integrifolia (Gaud.) Miq on IRS-1, Akt and Glut-4 in Fat-Fed C57BL/6J Type 2 Diabetes Mouse Model.Evid-Based Complement Alt Med 13 (3): 1-9 doi:10.1093/ecam/neq014.
52. Parekh VS, Umrani MR and Hardikar AA (2010) Taurine supports preservation of pro-endocrine cell types in human umbilical cord blood-derived mononuclear cells during cryostorage. Transplantation Proc, 42(10):4619-21
51. Joglekar MV and Hardikar AA (2010) Epithelial-to-mesenchymal transition in pancreatic islet beta cells. Cell Cycle 15;9(20):4077-9
50. Chayosumrit M, Hardikar AA and Sidhu K. Role of the Glucagon-like Peptide-1 Receptor Agonist in Maintaining Pluripotency in Human Embryonic Stem Cells. Open Stem Cells 2011; 3: 11-22
49. Joglekar MV, Wei CJ and Hardikar AA (2010) Quantitative estimation of multiple microRNAs and mRNAs from a single cell. Cold Spring Harbor Protocols 1;2010(8):pdb.prot5478. doi: 10.1101/pdb.prot5478 Cover story
48. Wu Y, Li J, Saleem S, Yee S, Hardikar AA, and Wang R (2010) C-Kit and stem cell factor regulate PANC-1 cell differentiation to insulin- and glucagon-producing cells. Lab investigation 90(9):1373-84
47. Khandwekar AP, Patil DP, Hardikar AA, Shouche YS, Doble M. (2010) In vivo modulation of foreign body response on polyurethane by surface entrapment technique. J Biomed Mater Res . 95(2):413-23
46. Sasikala M, Swapna G, Pavan K, Rao GV, Hardikar AA and Reddy DN (2010) Reduced expression of pdx-1 correlates with decreased beta cell function in chronic pancreatitis. Pancreas 39(6):856-62
45. Lee J, Jo J, Hardikar AA, Periwal V and Rane SG (2010) Cdk4 regulates recruitment of quiescent β-cells and ductal epithelial progenitors to reconstitute β-cell mass PLoS One 13;5(1):e8653
44. Phadnis SM, Ghaskadbi SM, Hardikar AA, Bhonde RR (2009) Mesenchymal stem cells derived from bone marrow of diabetic patients portrait unique markers influenced by the diabetic microenvironment. Rev Diabet Studies. 6(4):260-70.
43. Ranjan AK, Kumar U, Hardikar AA, Poddar P, Nair PD, Hardikar AA (2009) Human blood vessel-derived endothelial progenitors for endothelialization of small diameter vascular prosthesis. PLoS One 4(11):e7718.PMID: 19890388
42. Joglekar MV, Patil D, Joglekar VM, Rao GV, Reddy DN, Sasikala M, Shouche Y and Hardikar AA (2009) The miR-30 Family microRNAs Confer Epithelial Phenotype to Human Pancreatic Cells. Islets 1(2): 137 - 147. Cover story
41. Parekh VS, Joglekar MV and Hardikar AA (2009) Differentiation of human umbilical cord blood derived mononuclear cells to endocrine pancreatic lineage. Differentiation 78(4):232-40. Cover story
40. Joglekar MV, Joglekar VM, Joglekar SV and Hardikar AA (2009), Human fetal pancreatic insulin-producing cells proliferate in vitro. J Endocrinol 201(1):27-36, Epub 2009 May 6 Cover story
39. Sahu S*, Joglekar MV*, Dumbre R, Phadnis SM, Tosh D and Hardikar AA, (2009) Islet-like cell clusters occur naturally in human gall bladder and are retained in diabetic conditions J Cell Mol Med: 13(5):999-1000; *: equal first authors.
38. Joglekar MV, Joglekar VM and Hardikar AA (2009) Expression of islet-specific microRNAs during human pancreatic development. Gene Exp Pat ; 9(2): 109-113.
37. Dalvi MP, Umrani MR, Joglekar MV, Hardikar AA (2009) Human pancreatic islet progenitor cells demonstrate phenotypic plasticity in vitro. J Biosci 34(4):523-8.
36. Ranjan AK, Joglekar MV and Hardikar AA (2009) Endothelial cells in pancreatic islet development and function Islets 1(1); 2 – 9
35. Kode JA, Mukherjee S, Joglekar MV and Hardikar AA (2009) Mesenchymal Stem cells: Immunobiology and role in immunomodulation and tissue regeneration. Cytotherapy : 11(4):377-91
34. Joglekar MV, Parekh VS, Mehta S, Bhonde RR and Hardikar AA (2007) MicroRNA Profiling of Developing and Regenerating Pancreas Reveal Post-transcriptional Regulation of Neurogenin3. Dev Biol 311(2): 603-612
33. Joglekar MV, Parekh VS and Hardikar AA (2007) New Pancreas from Old: Microregulators of Pancreas Regeneration Trends Endocrinol Metab 18(10):393-400. Cover citation.
32. Phadnis SM*, Joglekar MV*, Venkateshan V, Ghaskadbi SM, Hardikar AA, Bhonde RR. (2006) Human umbilical cord blood serum promotes growth, proliferation, as well as differentiation of human bone marrow-derived progenitor cells. In Vitro Cell Dev Biol 42(10):283-6.
31. Hardikar AA, Lees JG, Sidhu KS, Colvin E and Tuch BE; Stem-Cell Therapy for Diabetes Cure: How Close Are We? (2006) Curr Stem Cell Res & Therapy : 1:425-436
30. Gershengorn MC, Geras-Raaka E, Hardikar AA, Raaka BM. (2005) Are better islet cell precursors generated by epithelial-to-mesenchymal transition? Cell Cycle . 4:380-382.
29. Gershengorn MC, Hardikar AA, Wei C, Geras-Raaka E, Marcus-Samuels B, Raaka BM (2004) Epithelial-to-Mesenchymal Transition Generates Proliferative Human Islet Precursor Cells. Science 306:2261-2264.
28. Hardikar AA (2004) Pancreas regeneration: Generating new pancreas from old. Trends Endocrinol Metab . 15:198-203 Cover story
27. Hardikar AA, Marcus-Samuels B, Geras-Raaka E, Raaka BM, Gershengorn MC (2003) Human pancreatic precursor cells secrete FGF2 to stimulate clustering into hormone-expressing islet-like cell aggregates. Proc Natl Acad Sci USA 100(12): 7117-7122.
26. Hardikar AA, Wang XY, Williams LJ, Kwok J, Wong R, Yao M, Tuch BE. (2002) Functional maturation of fetal porcine beta-cells by glucagon-like peptide 1 and cholecystokinin. Endocrinology ; 143:3505-3514.
25. Merezek S, Hardikar AA, Yajnik CS, Remacle C and Reusens B (2001) Intra-uterine protein malnutrition and diabetes: the role of sulphur amino acids. J Endocrinol ; 171:299-308.
24. Hardikar AA, Risbud MV, Remacle C, Reusens B, Hoet JJ, Bhonde RR. (2001) Islet cryopreservation: improved recovery following taurine pretreatment. Cell Transplantation; 10:247-253.
23. Hardikar AA, Nath BB. (2001) Chromosomal polymorphism is associated with nematode parasitism in a natural population of a tropical midge. Chromosoma ; 110: 58-64.
22. Risbud MV, Hardikar AA, Bhat SV, Bhonde RR. (2000) pH-sensitive freeze-dried chitosan-polyvinyl pyrrolidone hydrogels as controlled release system for antibiotic delivery. J Controlled Release ; 68: 23-30.
21. Hardikar AA, Risbud MV, Bhonde RR. (2000) Improved post-cryopreservation recovery following encapsulation of islets in chitosan-alginate microcapsules. Transplantation Proc; 32: 824-5.
20. Risbud M, Hardikar A, Bhonde R. (2000) Growth modulation of fibroblasts by chitosan-polyvinyl pyrrolidone hydrogel: implications for wound management? J Biosci; 25: 25-31.
19. Risbud M, Hardikar A, Bhonde R. (2000) Chitosan-polyvinyl pyrrolidone hydrogels as candidate for islet immunoisolation: in vitro biocompatibility evaluation. Cell Transplantation ; 9 : 25-31.
18. Hardikar AA, Bhonde RR. (1999) Modulating experimental diabetes by treatment with cytosolic extract from the regenerating pancreas. Diabetes Res Clin Pract; 46: 203-11.
17. Hardikar AA, Karandikar MS, Bhonde RR. (1999) Effect of partial pancreatectomy on diabetic status in BALB/c mice. J Endocrinol ; 162: 189-195.
16. Hardikar AA, Risbud MV and Bhonde RR (1999) A simple microcapsule generator design for islet encapsulation, J Biosci. 24 (3): 371 - 376.
Editorial /commentaries:
15. Hardikar AA, Walker M, Lynn FC (2013) Non-coding RNAs (Editorial) Exp Diabetes Res (2012)
14. Satoor SN and Hardikar AA (2013) Maternal nutrition, nutrient transfer and foetal pancreas development. Invited commentary in press In J Med Res
13. Joglekar MV, Parekh VS and Hardikar AA (2011) microRNAs in endocrine pancreas development, differentiation and disease. In J Exp Biology. (invited article in press)
12. Hardikar AA and Tosh D (2009) Commentary: β-cells in the lab. Nature India, doi 10:1038/nindia.2009.160 (http://www.nature.com/nindia/2009/090625/full/nindia.2009.160.html)
11. Sahu S, Tosh D and Hardikar AA (2009) Commentary: New sources of beta-cells for treating diabetes. J Endocrinology: 202(1):13-6
10. Hardikar A, (2004) Role of Incretins in Pancreas Growth and Development (Editorial) J Pancreas 5(6):454-456.
Chapters in books:
9. Sahu S, Joglekar M, Yang S and Hardikar AA (2011) Gallbladder-derived islet stem cells, In "Stem Cells", ISBN: 978-953-307-412-2. Open Access Publishers, Vienna, Austria.
8. Joglekar MV and Hardikar AA (2013) Human fetal pancreatic progenitor cells in: Clin Issues of Fetal Tissue Transplantation in Medicine. Chapter 18, pp 237-249. Editor: Phillip Stubblefield and Niranjan Bhattacharya. Publisher: Springer
7. Lie D, Chayosumrit M, Hardikar A and Sidhu K (2010) Puluripotent stem cells and diabetes: Basic Science to Clinical Applications in: Frontiers in Pluripotent Stem Cell Research : Bench-to-Bedside Publisher: Betham Press, Editor: K Sidhu
6. Joglekar MV, Ranjan AK and Hardikar AA (2009) Pancreas development and regeneration. “In Stem Cells: Organogenesis and Cancer” Editor: Dr. SR Singh, Book Editor & Managing Editor: Research Signpost/ Transworld Research Network press (http://www.ressign.com/). Frontiers in Bioscience, NIH, USA
5. Hardikar AA and Gershengorn MC (2003) Chapter 51: ‘Stem Cells’ in 3rd edition of ‘Diabetes Mellitus: A Fundamental and Clinical Text’, edited by: Dr. Derek LeRoith, Simeon I. Taylor and Jerrold M. Olefsky. 4. Shukla R, Risbud MR, Hardikar AA, Bhonde RR, (2004) Chitosan and chitin derivatives in islet immunoisolation and transplantation. In “Chitin and Chitosan: Opportunities and Challenges” Chapter 15, p 211-222, eds; Dutta PK
3. Wong W, Hardikar AA and Joglekar MV (2017) Generation of human islet progenitor cells via epithelial to mesenchymal transition, in Pancreatic islet Biology, Springer Humana press, eds Hardikar A, pp217-240.
Books:
2. “Pancreatic Islet Biology” (2016). Chief Editor: Hardikar AA, Publisher: Springer press, USA, ISSN 2196-8985, ISBN: 978-3-319-45305-7 (print version) / 978-3-319-45307-1. (e-book version). A textbook for diabetes researchers with 12 chapters from 45 authors over 336 pages of text. 1. “Progenitor Cells” (2018) Co-editor with Chief Editor Dr. Mugdha Joglekar, University of Sydney for a book in the well-known Methods in Molecular Biology book series published by Springer Press, USA.
89. Farr RJ, Wong WKM, Maynard C, Tersey SA, Mirmira RG, Hardikar AA and Joglekar MV (2019) Comparative analysis of diagnostic platforms for measurement of unmethylated / methylated insulin DNA. J Biol Meth (in press).
88. Poddar A, Joglekar MV, Hardikar AA and Shukla R (2019) A novel gene delivery approach using metal organic frameworks in human islet-derived cells Methods Mol Biol .(in press).
87. Maynard CL, Wong WKM, Hardikar AA and Joglekar MV (2019) Droplet digital PCR for measuring absolute copies of gene transcripts in human islet-derived progenitor Cells Methods Mol Biol .(in press).
86. Slykerman R, Joglekar M, Hardikar A Satoor S, Thompson JM, Jenkins AJ, Mitchell EA, Murphy R (2019) Maternal stress during pregnancy and small for gestational age birthweight are not associated with telomere length at 11 years of age. Gene 694:97-101. doi: 10.1016/j.gene.2019.01.017. Epub 2019 Feb 7.
85. Williams MD, Joglekar MV, Satoor SN, Wong WKM, Keramidaris E, Rixon A, O’Connell P, Hawthorne WJ, Mitchell GM and Hardikar AA (2018) Epigenetic and transcriptome profiling identifies a population of visceral adipose-derived progenitor cells with potential to differentiate into endocrine pancreatic lineage; Cell Transplantation 28(1):89-104. doi: 10.1177/0963689718808472. Epub 2018 Oct 30.
84. Joglekar MV, Sorensen A, Wong KM, Hardikar AA, Dalgaard LT (2018) Non-coding RNAs in islet β-cell maturation and development; Noncoding RNA 4(4). pii: E41. doi: 10.3390/ncrna4040041..
83. Joglekar MV, Wong WKM, Maynard C, Umrani MR, Martin D, Loudovaris T, Thomas HE, Dalgaard LT and Hardikar AA (2018) Expression of miR-206 in human islets and its role in glucokinase regulation. Am J Physiol – Endocrinol Metab.;315(4):E634-E637. doi: 10.1152/ajpendo.00152.2018 82. Hakami NY, Ranjan AK, Hardikar AA, Dusting GJ, Peshavariya HM (2017) Role of NADPH Oxidase-4 in Human Endothelial Progenitor Cells. Frontiers Physiol. 23;8:150. 81. Umrani MR, Joglekar MV, Somerville Glover E, Wong W and Hardikar AA (2017) Connexins and microRNAs: interlinked players in regulating islet function? Islets; 3;9(5):99-108
80. Joglekar MV, Trivedi PM, Kay TW, Hawthorne WJ, O'Connell PJ, Jenkins AJ, Hardikar AA, Thomas HE. (2016) Human islet cells are killed by BID-independent mechanisms in response to FAS ligand Apoptosis; 21(4):379-89. doi: 10.1007/s10495-016-1212-y.PMID: 26758067
79. Joglekar MV, Januszewski AS, Jenkins AJ, Hardikar AA. (2016) Circulating microRNA Biomarkers of Diabetic Retinopathy.Diabetes.;65(1):22-4. doi: 10.2337/dbi15-0028. PMID: 26696637
78. Jenkins AJ, Joglekar MV, Hardikar AA, Keech AC, O'Neal DN, Januszewski AS (2015) Biomarkers in Diabetic Retinopathy. Rev Diabet Stud. Spring-Summer;12(1-2):159-95. doi: 10.1900/RDS.2015.12.159. Epub 2015 Aug 10.PMID: 26676667
77. Farr RJ, Joglekar MV, Hardikar AA.(2015) Circulating microRNAs in Diabetes Progression: Discovery, Validation, and Research Translation. EXS. 2015;106:215-44. doi: 10.1007/978-3-0348-0955-9_10. PMID: 26608206
76. Kim KW, Ho A, Alshabee-Akil A, Hardikar AA, Kay TW, Rawlinson WD, Craig ME.(2015) Coxsackievirus B5 Infection Induces Dysregulation of MicroRNAs Predicted to Target Known Type 1 Diabetes Risk Genes in Human Pancreatic Islets. Diabetes*. 2015 Nov 11. pii: db150956.
*Also special commentary in Nature Reviews - Endocrinol & Metab
75. Hardikar AA1,°, Satoor SN°, Karandikar MS°, Joglekar MV° et al.. (2015) Susceptibility to obesity and diabetes following multigeneration undernutrition is not reversed by two generations of nutrient availability. Cell Metabolism (PMID: 26166746); 1 AAH – First and corresponding author, ° equal contribution amongst 19 authors (Cover story).
74. Farr RJ, Januszewski AS, Joglekar MV, Liang H, McAulley AK, Hewitt AW, Thomas HE, Loudovaris T, Kay TW, Jenkins A, Hardikar AA (2015) A comparative analysis of high-throughput platforms for validation of a circulating microRNA signature in diabetic retinopathy. Sci Rep 2;5:10375. www.nature.com/srep; doi: 10.1038/srep10375.
73. Wong W, Farr RJ, Joglekar MV, Januszewski AS, Hardikar AA (press) Probe-based real-time PCR approaches for quantitative measurement of microRNAs. J Vis Exp 14;(98). doi: 10.3791/52586
72. Liu J, Joglekar MV, Sumer H, Hardikar AA, Teede H, Verma PJ (2015) Integration-Free Human Induced Pluripotent Stem Cells from Type 1 Diabetes Patient Skin Fibroblasts Show Upregulation of Pancreas-Specific microRNAs, Cell Medicine; 7(1): 15-24
71. Hardikar AA, Farr RJ, Joglekar MV (2014) Circulating microRNAs: Understanding the limits for quantitative measurement by real-time PCR J Am Heart Assoc. 3(1): e000792. doi: 10.1161/JAHA.113.000792.
70. Williams MD, Wong W, Rixon A, Satoor SN, Hardikar AA, Joglekar MV. (2014) Pdx1 (GFP/w) mice for isolation, characterization, and differentiation of pancreatic progenitor cells. Methods Mol Biol , 1194:271-88. doi: 10.1007/978-1-4939-1215-5_15.
69. Satoor SN, Patil DP, Kristensen HD, Joglekar MV, Shouche Y, Hardikar AA. (2014) Manipulation and assessment of gut microbiome for metabolic studies. Methods Mol Biol 1194:449-69. doi: 10.1007/978-1-4939-1215-5_26.
68. Hardikar AA: on behalf of the RAPID Study group (2013) microRNAs in Pancreatic Beta Cells: from Cradle to the Grave Pediatric Endocrinology Reviews; 11(1):14-20.
67. Sundrani DP, Reddy US, Joshi AA, Mehendale SS, Chavan-Gautam PM, Hardikar AA, Chandak GR, Joshi SR (2013) Differential placental methylation and expression of VEGF, FLT-1 and KDR genes in human term and preterm preeclampsia. Clinical Epigenetics. 26;5(1):6. doi: 10.1186/1868-7083-5-6.
66. Satoor SN and Hardikar AA (2013) Maternal nutrition, nutrient transfer & foetal pancreas development. In J Med Res.;137(2):249-50.
65. Hardikar AA, Walker MD, Lynn F (2012) Non-codimng RNAs. Exp Diabetes Res. 629249. doi: 10.1155/2012/629249.
64. Ranjan AK, Joglekar MV, Atre AN, Patole M, Bhonde RR and Hardikar AA (2012) Simultaneous Imaging of microRNA / mRNA Territories with Protein Territory in Mammalian Cells at Single Cell Resolution. RNA Biology 9:7, 949-53. doi: 10.4161/rna.20484
63. Ranjan AK, Joglekar MV, Atre AN, Patole M, Bhonde RR and Hardikar AA (2012) Cellular detection of multiple antigens at single cell resolution using antibodies generated from the same species. J Immunol Methods 379(1-2):42-7. doi: 10.1016/j.jim.2012.02.018. Epub 2012 Mar 4.
62. Joglekar MV and Hardikar AA (2012) Isolation, characterization and expansion of islet-derived progenitor cells. Methods Mol Biol 879:351-66. doi: 10.1007/978-1-61779-815-3_21.
61. Kumar U, Ranjan AK, Chandrashekhar S, Hardikar AA, Pundle A and Poddar P. (2012) Green approach towards size controlled synthesis of biocompatible antibacterial metal nanoparticles in aqueous phase using lysozyme. Current Nanoscience 8(1), 130-140(11)
60. Vaithilingam V, Quayum N, Joglekar MV, Jensen J, Hardikar AA, Oberholzer J, Guillemin GJ, PhD, Tuch BE (2011) Effect of alginate encapsulation on the cellular transcriptome of human islets. Biomaterials 32(33):8416-25
59. Satoor SN, Puranik AS, Kumar S, Williams MD, Ghale M, Rahalkar A, Karandikar MS, Shouche Y, Patole M, Bhonde RR, Yajnik CS and Hardikar AA (2011) Location, location, location: Beneficial effects of autologous fat transplantation. Sci Rep 2011;1:81. (http://www.nature.com/srep/2011/110902/srep00081/full/srep00081.html)
58. Ansarullah, Bhavna Bharucha, Mitesh Dwivedi, Naresh C Laddha, Rasheedunnisa Begum, Anandwardhan A Hardikar and A V Ramachandran (2011) Antioxidant rich flavonoids from Oreocnide integrifolia enhance glucose uptake and insulin secretion and protects pancreatic beta-cells from streptozotocin insult. BMC Comp Alt Med 12;11:126. doi: 10.1186/1472-6882-11-126.
57. Ansarullah, Bhavna Bharucha, Malati Umarani, Mitesh Dwivedi, Naresh C Laddha, Rasheedunissa Begum, Anandwardhan A Hardikar, and Ramachandran A.V (2011) Oreocnide integrifolia flavonoids augment reprogramming for islet neogenesis and ß-cell regeneration in pancreatectomized BALB/c mice Evid-Based Complement Alt Med 260467. doi: 10.1155/2012/260467.
56. Forster N, Penington A, Hardikar AA, Palmer J, Hussey A, Taj J, Morrison W, Feeney S (2011) A prevascularised tissue engineering chamber supports growth and function of islets and progenitor cells in diabetic mice, Islets 3(5):271-83.
55. Williams MD, Mitchell GM and Hardikar AA (2011) Stem cells: Epigenetic basis of differentiation Open Stem Cells 3:28-33
54. Phadnis SM, Joglekar MV, Dalvi1 MP, Muthyala S, Nair PD, Ghaskadbi SM, Bhonde RR and Hardikar AA (2011) Human bone marrow-derived mesenchymal cells differentiate and mature into endocrine pancreatic lineage in vivo. Cytotherapy 13(3): 279-293 Cover story
53. Ansarullah, Jayaraman S, Hardikar AA and Ramachandran AV (2011) Influence of Oreocnide integrifolia (Gaud.) Miq on IRS-1, Akt and Glut-4 in Fat-Fed C57BL/6J Type 2 Diabetes Mouse Model.Evid-Based Complement Alt Med 13 (3): 1-9 doi:10.1093/ecam/neq014.
52. Parekh VS, Umrani MR and Hardikar AA (2010) Taurine supports preservation of pro-endocrine cell types in human umbilical cord blood-derived mononuclear cells during cryostorage. Transplantation Proc, 42(10):4619-21
51. Joglekar MV and Hardikar AA (2010) Epithelial-to-mesenchymal transition in pancreatic islet beta cells. Cell Cycle 15;9(20):4077-9
50. Chayosumrit M, Hardikar AA and Sidhu K. Role of the Glucagon-like Peptide-1 Receptor Agonist in Maintaining Pluripotency in Human Embryonic Stem Cells. Open Stem Cells 2011; 3: 11-22
49. Joglekar MV, Wei CJ and Hardikar AA (2010) Quantitative estimation of multiple microRNAs and mRNAs from a single cell. Cold Spring Harbor Protocols 1;2010(8):pdb.prot5478. doi: 10.1101/pdb.prot5478 Cover story
48. Wu Y, Li J, Saleem S, Yee S, Hardikar AA, and Wang R (2010) C-Kit and stem cell factor regulate PANC-1 cell differentiation to insulin- and glucagon-producing cells. Lab investigation 90(9):1373-84
47. Khandwekar AP, Patil DP, Hardikar AA, Shouche YS, Doble M. (2010) In vivo modulation of foreign body response on polyurethane by surface entrapment technique. J Biomed Mater Res . 95(2):413-23
46. Sasikala M, Swapna G, Pavan K, Rao GV, Hardikar AA and Reddy DN (2010) Reduced expression of pdx-1 correlates with decreased beta cell function in chronic pancreatitis. Pancreas 39(6):856-62
45. Lee J, Jo J, Hardikar AA, Periwal V and Rane SG (2010) Cdk4 regulates recruitment of quiescent β-cells and ductal epithelial progenitors to reconstitute β-cell mass PLoS One 13;5(1):e8653
44. Phadnis SM, Ghaskadbi SM, Hardikar AA, Bhonde RR (2009) Mesenchymal stem cells derived from bone marrow of diabetic patients portrait unique markers influenced by the diabetic microenvironment. Rev Diabet Studies. 6(4):260-70.
43. Ranjan AK, Kumar U, Hardikar AA, Poddar P, Nair PD, Hardikar AA (2009) Human blood vessel-derived endothelial progenitors for endothelialization of small diameter vascular prosthesis. PLoS One 4(11):e7718.PMID: 19890388
42. Joglekar MV, Patil D, Joglekar VM, Rao GV, Reddy DN, Sasikala M, Shouche Y and Hardikar AA (2009) The miR-30 Family microRNAs Confer Epithelial Phenotype to Human Pancreatic Cells. Islets 1(2): 137 - 147. Cover story
41. Parekh VS, Joglekar MV and Hardikar AA (2009) Differentiation of human umbilical cord blood derived mononuclear cells to endocrine pancreatic lineage. Differentiation 78(4):232-40. Cover story
40. Joglekar MV, Joglekar VM, Joglekar SV and Hardikar AA (2009), Human fetal pancreatic insulin-producing cells proliferate in vitro. J Endocrinol 201(1):27-36, Epub 2009 May 6 Cover story
39. Sahu S*, Joglekar MV*, Dumbre R, Phadnis SM, Tosh D and Hardikar AA, (2009) Islet-like cell clusters occur naturally in human gall bladder and are retained in diabetic conditions J Cell Mol Med: 13(5):999-1000; *: equal first authors.
38. Joglekar MV, Joglekar VM and Hardikar AA (2009) Expression of islet-specific microRNAs during human pancreatic development. Gene Exp Pat ; 9(2): 109-113.
37. Dalvi MP, Umrani MR, Joglekar MV, Hardikar AA (2009) Human pancreatic islet progenitor cells demonstrate phenotypic plasticity in vitro. J Biosci 34(4):523-8.
36. Ranjan AK, Joglekar MV and Hardikar AA (2009) Endothelial cells in pancreatic islet development and function Islets 1(1); 2 – 9
35. Kode JA, Mukherjee S, Joglekar MV and Hardikar AA (2009) Mesenchymal Stem cells: Immunobiology and role in immunomodulation and tissue regeneration. Cytotherapy : 11(4):377-91
34. Joglekar MV, Parekh VS, Mehta S, Bhonde RR and Hardikar AA (2007) MicroRNA Profiling of Developing and Regenerating Pancreas Reveal Post-transcriptional Regulation of Neurogenin3. Dev Biol 311(2): 603-612
33. Joglekar MV, Parekh VS and Hardikar AA (2007) New Pancreas from Old: Microregulators of Pancreas Regeneration Trends Endocrinol Metab 18(10):393-400. Cover citation.
32. Phadnis SM*, Joglekar MV*, Venkateshan V, Ghaskadbi SM, Hardikar AA, Bhonde RR. (2006) Human umbilical cord blood serum promotes growth, proliferation, as well as differentiation of human bone marrow-derived progenitor cells. In Vitro Cell Dev Biol 42(10):283-6.
31. Hardikar AA, Lees JG, Sidhu KS, Colvin E and Tuch BE; Stem-Cell Therapy for Diabetes Cure: How Close Are We? (2006) Curr Stem Cell Res & Therapy : 1:425-436
30. Gershengorn MC, Geras-Raaka E, Hardikar AA, Raaka BM. (2005) Are better islet cell precursors generated by epithelial-to-mesenchymal transition? Cell Cycle . 4:380-382.
29. Gershengorn MC, Hardikar AA, Wei C, Geras-Raaka E, Marcus-Samuels B, Raaka BM (2004) Epithelial-to-Mesenchymal Transition Generates Proliferative Human Islet Precursor Cells. Science 306:2261-2264.
28. Hardikar AA (2004) Pancreas regeneration: Generating new pancreas from old. Trends Endocrinol Metab . 15:198-203 Cover story
27. Hardikar AA, Marcus-Samuels B, Geras-Raaka E, Raaka BM, Gershengorn MC (2003) Human pancreatic precursor cells secrete FGF2 to stimulate clustering into hormone-expressing islet-like cell aggregates. Proc Natl Acad Sci USA 100(12): 7117-7122.
26. Hardikar AA, Wang XY, Williams LJ, Kwok J, Wong R, Yao M, Tuch BE. (2002) Functional maturation of fetal porcine beta-cells by glucagon-like peptide 1 and cholecystokinin. Endocrinology ; 143:3505-3514.
25. Merezek S, Hardikar AA, Yajnik CS, Remacle C and Reusens B (2001) Intra-uterine protein malnutrition and diabetes: the role of sulphur amino acids. J Endocrinol ; 171:299-308.
24. Hardikar AA, Risbud MV, Remacle C, Reusens B, Hoet JJ, Bhonde RR. (2001) Islet cryopreservation: improved recovery following taurine pretreatment. Cell Transplantation; 10:247-253.
23. Hardikar AA, Nath BB. (2001) Chromosomal polymorphism is associated with nematode parasitism in a natural population of a tropical midge. Chromosoma ; 110: 58-64.
22. Risbud MV, Hardikar AA, Bhat SV, Bhonde RR. (2000) pH-sensitive freeze-dried chitosan-polyvinyl pyrrolidone hydrogels as controlled release system for antibiotic delivery. J Controlled Release ; 68: 23-30.
21. Hardikar AA, Risbud MV, Bhonde RR. (2000) Improved post-cryopreservation recovery following encapsulation of islets in chitosan-alginate microcapsules. Transplantation Proc; 32: 824-5.
20. Risbud M, Hardikar A, Bhonde R. (2000) Growth modulation of fibroblasts by chitosan-polyvinyl pyrrolidone hydrogel: implications for wound management? J Biosci; 25: 25-31.
19. Risbud M, Hardikar A, Bhonde R. (2000) Chitosan-polyvinyl pyrrolidone hydrogels as candidate for islet immunoisolation: in vitro biocompatibility evaluation. Cell Transplantation ; 9 : 25-31.
18. Hardikar AA, Bhonde RR. (1999) Modulating experimental diabetes by treatment with cytosolic extract from the regenerating pancreas. Diabetes Res Clin Pract; 46: 203-11.
17. Hardikar AA, Karandikar MS, Bhonde RR. (1999) Effect of partial pancreatectomy on diabetic status in BALB/c mice. J Endocrinol ; 162: 189-195.
16. Hardikar AA, Risbud MV and Bhonde RR (1999) A simple microcapsule generator design for islet encapsulation, J Biosci. 24 (3): 371 - 376.
Editorial /commentaries:
15. Hardikar AA, Walker M, Lynn FC (2013) Non-coding RNAs (Editorial) Exp Diabetes Res (2012)
14. Satoor SN and Hardikar AA (2013) Maternal nutrition, nutrient transfer and foetal pancreas development. Invited commentary in press In J Med Res
13. Joglekar MV, Parekh VS and Hardikar AA (2011) microRNAs in endocrine pancreas development, differentiation and disease. In J Exp Biology. (invited article in press)
12. Hardikar AA and Tosh D (2009) Commentary: β-cells in the lab. Nature India, doi 10:1038/nindia.2009.160 (http://www.nature.com/nindia/2009/090625/full/nindia.2009.160.html)
11. Sahu S, Tosh D and Hardikar AA (2009) Commentary: New sources of beta-cells for treating diabetes. J Endocrinology: 202(1):13-6
10. Hardikar A, (2004) Role of Incretins in Pancreas Growth and Development (Editorial) J Pancreas 5(6):454-456.
Chapters in books:
9. Sahu S, Joglekar M, Yang S and Hardikar AA (2011) Gallbladder-derived islet stem cells, In "Stem Cells", ISBN: 978-953-307-412-2. Open Access Publishers, Vienna, Austria.
8. Joglekar MV and Hardikar AA (2013) Human fetal pancreatic progenitor cells in: Clin Issues of Fetal Tissue Transplantation in Medicine. Chapter 18, pp 237-249. Editor: Phillip Stubblefield and Niranjan Bhattacharya. Publisher: Springer
7. Lie D, Chayosumrit M, Hardikar A and Sidhu K (2010) Puluripotent stem cells and diabetes: Basic Science to Clinical Applications in: Frontiers in Pluripotent Stem Cell Research : Bench-to-Bedside Publisher: Betham Press, Editor: K Sidhu
6. Joglekar MV, Ranjan AK and Hardikar AA (2009) Pancreas development and regeneration. “In Stem Cells: Organogenesis and Cancer” Editor: Dr. SR Singh, Book Editor & Managing Editor: Research Signpost/ Transworld Research Network press (http://www.ressign.com/). Frontiers in Bioscience, NIH, USA
5. Hardikar AA and Gershengorn MC (2003) Chapter 51: ‘Stem Cells’ in 3rd edition of ‘Diabetes Mellitus: A Fundamental and Clinical Text’, edited by: Dr. Derek LeRoith, Simeon I. Taylor and Jerrold M. Olefsky. 4. Shukla R, Risbud MR, Hardikar AA, Bhonde RR, (2004) Chitosan and chitin derivatives in islet immunoisolation and transplantation. In “Chitin and Chitosan: Opportunities and Challenges” Chapter 15, p 211-222, eds; Dutta PK
3. Wong W, Hardikar AA and Joglekar MV (2017) Generation of human islet progenitor cells via epithelial to mesenchymal transition, in Pancreatic islet Biology, Springer Humana press, eds Hardikar A, pp217-240.
Books:
2. “Pancreatic Islet Biology” (2016). Chief Editor: Hardikar AA, Publisher: Springer press, USA, ISSN 2196-8985, ISBN: 978-3-319-45305-7 (print version) / 978-3-319-45307-1. (e-book version). A textbook for diabetes researchers with 12 chapters from 45 authors over 336 pages of text. 1. “Progenitor Cells” (2018) Co-editor with Chief Editor Dr. Mugdha Joglekar, University of Sydney for a book in the well-known Methods in Molecular Biology book series published by Springer Press, USA.